
Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
Prescription required
Itraconazole (200mg)
Zyitra 200 Capsule is used for treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Zyitra 200 Capsule contains Itraconazole (200mg). It belongs to the Azole antifungal (triazole) class of medicines.
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of Zyitra as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more Zyitra than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Zyitra are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended (especially in pregnancy); use only if clearly needed and prescribed. |
|---|---|
| Breastfeeding | Zyitra 200 Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Use with caution; avoid excessive alcohol due to increased risk of liver toxicity. |
| Kidney | There is limited information available on the use of Zyitra 200 Capsule in patients with kidney disease. Please consult your doctor. |
| Liver | There is limited information available on the use of Zyitra 200 Capsule in patients with liver disease. Please consult your doctor.<br>Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine. |
| Habit forming | No |
Prescription-only antifungal. Can cause serious liver injury—seek help for yellowing of eyes/skin, dark urine, severe fatigue or abdominal pain; liver function monitoring may be needed. May worsen heart failure (negative inotropic effect)—avoid/use with extreme caution in patients with congestive heart failure. Numerous drug interactions via CYP3A4—some combinations are contraindicated due to risk of serious heart rhythm problems. Use caution in kidney/liver disease and in elderly.
Contraindicated/major interactions with drugs highly dependent on CYP3A4: simvastatin/lovastatin, certain antiarrhythmics (e.g., quinidine, dofetilide), ergot alkaloids, cisapride, pimozide; increases levels of warfarin, digoxin, cyclosporine/tacrolimus, certain benzodiazepines, calcium channel blockers; reduced absorption with PPIs/H2 blockers/antacids; rifampicin/rifabutin/phenytoin/carbamazepine reduce itraconazole levels.
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack and out of reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Zyitra 200 Capsule helps treat fungal infections of mouth, skin, vagina or any other parts of the body.</li> <li>Do not skip any doses and finish the full course of treatment even if you feel better.</li> <li>Take it with food, preferably at the same time everyday.</li> <li>Use a reliable method of contraception to prevent pregnancy while taking this medicine.</li> <li>Do not take indigestion remedies (antacids) within two hours of taking Zyitra 200 Capsule .</li> <li>Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.</li> <li>Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Itraconazole (200mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zyitra 200 Capsule |
|---|---|---|---|
| Itraleaf-200 mg CapsuleRISEMARKER PHARMACEUTICALS | capsule · 4`S | ₹68 | 79% more |
| Itzo 200 CapsuleDEE GRADIBUS LIFE CARE (P) LTD | capsule · 4`S | ₹83 | 121% more |
| Itrasys 200 mg TabletSYSTOPIC LAB | tablet · 4`S | ₹90 | 137% more |
| Mycocure 100 mg CapsuleKAIZEN LABORATORIES PVT LTD.` | capsule · 10`S | ₹94 | 148% more |
| Itrabond 200 mgBrinton Pharmaceuticals Pvt Ltd | 7`S | ₹165 | 338% more |
| Itoral 100 mg CapsulePUREDERMA HEALTHCARE | capsule · 10`S | ₹175 | 363% more |
| Logispor-200 mg CapsuleCanixa Life Sciences Pvt. Ltd. | capsule · 10`S | ₹190 | 404% more |
| Nixitral 200Canixa Life Sciences Pvt. Ltd. | 10`S | ₹190 | 404% more |
| Izofung 200 mg CapsuleEMBARK PHARMACEUTICALS | capsule · 10`S | ₹220 | 483% more |
| Panitra 200 mg CapsuleEAST WEST PHARMA | capsule · 10`S | ₹224 | 493% more |
| Itzoft 200 mg CapsuleNUFACE PHARMA | capsule · 10`S | ₹230 | 510% more |
| Zotinea 200 mg CapsuleBDR PHARMACEUTICALS INTERNATIO | capsule · 10 | ₹231 | 512% more |

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The information on Zyitra 200 Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.