
Actibile 150MG Tab
ZYDUS HEALTHCARE PHARMA - tablet - 150 mg - 10 S
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Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026
Itraconazole (200mg)
Treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
Common side effects of Zyitra 200 Caps may include:

ZYDUS HEALTHCARE PHARMA - tablet - 150 mg - 10 S
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Prescription-only antifungal. Can cause serious liver injury—seek help for yellowing of eyes/skin, dark urine, severe fatigue or abdominal pain; liver function monitoring may be needed. May worsen heart failure (negative inotropic effect)—avoid/use with extreme caution in patients with congestive heart failure. Numerous drug interactions via CYP3A4—some combinations are contraindicated due to risk of serious heart rhythm problems. Use caution in kidney/liver disease and in elderly.