Corbis Am 2.5/2.5MG Tab

Tablet

Treatment of hypertension (high blood pressure); may also be used in patients with stable angina when combination therapy is appropriate.

Amlodipine is a calcium channel blocker that relaxes blood vessels, lowering blood pressure and reducing cardiac workload. Bisoprolol is a cardioselective beta-blocker that slows heart rate and reduces the force of contraction, helping control blood pressure and angina symptoms.

Tablet for oral use. Take exactly as prescribed, usually once daily at the same time each day, with or without food. Do not stop suddenly without medical advice.

dizziness, headache, fatigue, slow heart rate (bradycardia), low blood pressure, swelling of ankles/feet (peripheral edema), flushing, nausea

Use with caution in heart failure, conduction disorders (AV block), bradycardia, severe hypotension, asthma/COPD (may worsen breathing), diabetes (may mask hypoglycaemia symptoms), thyroid disorders (may mask symptoms), liver impairment (amlodipine), and severe peripheral vascular disease. Do not stop beta-blocker abruptly (risk of rebound angina/HTN). Seek urgent help for severe dizziness/fainting, wheeze, chest pain worsening, or swelling of face/lips (allergy).

Other antihypertensives (additive BP lowering), verapamil/diltiazem/amiodarone/digoxin (increased bradycardia/heart block risk), clonidine (rebound hypertension on withdrawal), NSAIDs (may reduce antihypertensive effect), CYP3A4 inhibitors/inducers affecting amlodipine (e.g., clarithromycin, azole antifungals, grapefruit juice; rifampicin, carbamazepine, phenytoin), alcohol (increases dizziness/low BP), insulin/oral antidiabetics (masked hypoglycaemia), beta-agonist bronchodilators (reduced effect).

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Concor AM 2.5 Tablet, Bisoprolol AM 2.5 Tablet, Biso AM 2.5 Tablet, Bizotel AM 2.5 Tablet, Bicor AM 2.5 Tablet