Esam 5MG Tab 10S

Tablet

Treatment of hypertension (high blood pressure), treatment of chronic stable angina and vasospastic (Prinzmetal) angina

Amlodipine is a dihydropyridine calcium channel blocker that relaxes blood vessels by inhibiting calcium entry into vascular smooth muscle. This lowers blood pressure and reduces the workload on the heart, improving blood flow and relieving angina.

Take orally as prescribed, usually once daily at the same time each day, with or without food. Swallow whole with water; do not stop suddenly without medical advice.

ankle/leg swelling (edema), headache, dizziness, flushing, palpitations, fatigue, nausea

Use with caution in liver disease (may require dose adjustment). May cause dizziness or low blood pressure—use caution while driving or standing up quickly. In patients with severe aortic stenosis or heart failure, use only under medical supervision. Do not discontinue without consulting your doctor; monitor blood pressure regularly.

Other antihypertensives (additive BP lowering), simvastatin (limit simvastatin dose; increased levels), strong CYP3A4 inhibitors (e.g., clarithromycin, ketoconazole, ritonavir) may increase amlodipine levels, CYP3A4 inducers (e.g., rifampicin, phenytoin, carbamazepine) may reduce effect, grapefruit juice (may increase levels in some patients)

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

Amlodipine 5 mg Tablet, Amlokind 5 Tablet, Amlodac 5 Tablet, Stamlo 5 Tablet, Amodep 5 Tablet