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Prescription requiredEmcure PharmaAntidiabetic

Amaryl M 2 Tablet

Glimepiride 2 mg + Metformin (sustained release) 500 mg

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Amaryl M 2 Tablet is used for type 2 diabetes mellitus (to control high blood sugar) when diet and exercise alone are not sufficient.

Licensed pharmacyPharmacist-verified order

Key details

Salt: Glimepiride 2 mg + Metformin (sustained release) 500 mg
Available variants: tablet 20 Tablet
Price: ₹453 (₹22.67 per tablet)
Prescription: Required
Manufacturer: EMCURE PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Amaryl M 2 Tablet

Amaryl M 2 Tablet contains Glimepiride 2 mg + Metformin (sustained release) 500 mg. It belongs to the Sulfonylurea + Biguanide class of medicines.

Uses of Amaryl M 2 Tablet

  • Type 2 diabetes mellitus (to control high blood sugar) when diet
  • Exercise alone are not sufficient

Benefits of Amaryl M 2 Tablet

In Type 2 diabetes
Amaryl M prompts your pancreas to release more insulin, bringing high sugar readings down quickly. Steady control lowers the long-term risk of damage to the eyes, kidneys, nerves and blood vessels.

How Amaryl M 2 Tablet works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin reduces glucose production in the liver and improves insulin sensitivity, helping the body use insulin better. Together they lower fasting and post-meal blood glucose.

How to take Amaryl M 2 Tablet

Take exactly as prescribed by your doctor. Usually taken once daily with/after food (preferably with breakfast) to reduce stomach upset and risk of low sugar. Swallow the tablet whole; do not crush or chew (SR). Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Amaryl M 2 Tablet

Most side effects of Amaryl M are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Hypoglycaemia (low blood sugar)
  • nausea
  • diarrhoea
  • abdominal pain
  • vomiting
  • headache
  • dizziness
  • metallic taste
  • weight gain

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Amaryl M 2 Tablet

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyUNSAFE
Consult doctor (not recommended; insulin is generally preferred in pregnancy)
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCONSULT YOUR DOCTOR
Consult your doctor if you have kidney disease.
LiverCONSULT YOUR DOCTOR
Consult your doctor if you have liver disease.

Warnings and precautions

Risk of hypoglycaemia (especially with missed meals, strenuous exercise, or alcohol); carry sugar/glucose. Metformin can rarely cause lactic acidosis—risk increases in kidney or liver disease, severe infection, dehydration, heavy alcohol use, or low oxygen states; avoid in severe renal impairment and temporarily stop during severe illness. Inform doctor before surgery or iodinated contrast scans (may need to stop metformin). Monitor kidney function and vitamin B12 with long-term use. Use caution in elderly and those with irregular eating habits.

Do not take Amaryl M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia symptoms), corticosteroids and thiazide diuretics (raise blood sugar), ACE inhibitors (may increase hypoglycaemia), rifampicin (reduces effect), azole antifungals/clarithromycin (increase hypoglycaemia risk), iodinated contrast media (lactic acidosis risk with metformin), cimetidine (increases metformin levels)

How to store Amaryl M 2 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Quick tips for Amaryl M 2 Tablet

  • Take it shortly before a meal, and eat that meal.
  • Check your sugar as often as your doctor has asked, especially when your routine changes.
  • Take it with or just after food to reduce stomach upset.
  • Keep taking it even when your sugar readings look normal.
  • That is the medicine working.
  • Continue your diet and physical activity; this medicine works alongside them, not instead of them.

People taking Amaryl M are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
EMCURE PHARMA
Therapeutic class:
Antidiabetic
Drug class:
Sulfonylurea + Biguanide

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Amaryl M 2 Tablet FAQs

What is Amaryl M 2 Tablet used for?
Amaryl M 2 Tablet is commonly used for Type 2 diabetes mellitus (to control high blood sugar) when diet and exercise alone are not sufficient. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Amaryl M 2 Tablet?
Type 2 diabetes: Amaryl M prompts your pancreas to release more insulin, bringing high sugar readings down quickly. Steady control lowers the long-term risk of damage to the eyes, kidneys, nerves and blood vessels.
What is the salt in Amaryl M 2 Tablet?
Amaryl M 2 Tablet contains Glimepiride 2 mg + Metformin (sustained release) 500 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Amaryl M 2 Tablet?
Take exactly as prescribed by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Amaryl M 2 Tablet work?
Glimepiride (a sulfonylurea) increases insulin release from the pancreas.
Is Amaryl M 2 Tablet a prescription medicine?
Yes. Amaryl M 2 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Amaryl M 2 Tablet?
The side effects reported most often with Amaryl M are Hypoglycaemia (low blood sugar), nausea, diarrhoea, abdominal pain, vomiting. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Amaryl M 2 Tablet be taken during pregnancy?
Amaryl M 2 Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Amaryl M.
Can I drink alcohol while taking Amaryl M 2 Tablet?
No. Do not drink alcohol while taking Amaryl M 2 Tablet.
What if I miss a dose of Amaryl M 2 Tablet?
Take it as soon as you remember.
Is Amaryl M 2 Tablet habit forming?
No. Amaryl M 2 Tablet is not known to be habit forming when taken as prescribed.
How much does Amaryl M 2 Tablet cost on PingMeDoc Pharmacy?
Amaryl M 2 Tablet starts at ₹453 on PingMeDoc Pharmacy. Available in tablet 20 Tablet. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Amaryl M 2 Tablet?
Amaryl M 2 Tablet is manufactured by EMCURE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Amaryl M 2 Tablet delivered?
Amaryl M 2 Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Amaryl M 2 Tablet, Quick facts

Salt
Glimepiride 2 mg + Metformin (sustained release) 500 mg
Form
tablet
Price
₹453 (₹22.67 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
EMCURE PHARMA
Manufacturer
EMCURE PHARMA
Therapeutic class
Antidiabetic
Drug class
Sulfonylurea + Biguanide
Habit forming
No
Variants
tablet 20 Tablet
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. Manufacturer labeling/package insert
  2. CDSCO guidance and safety alerts, established medical literature (standard pharmacology texts)
  3. Indian clinical practice references
  4. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  5. National List of Essential Medicines (NLEM) 2022, Government of India.
  6. Manufacturer's package insert / prescribing information for Amaryl M 2 Tablet.
  7. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.