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Biological E Ltd - 0.5 ml - 10 X0.5 ml
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Methylcobalamin (500mcg) + Thiamine(Vitamin B1) (50mg) + Vitamin B6 (Pyridoxine) (50mg) + Nicotinamide (50mg) + D-Panthenol (25mg)
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Bethadoxin-12 Injection is used for nutritional deficiencies.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Bethadoxin-12 Injection contains Methylcobalamin (500mcg) + Thiamine(Vitamin B1) (50mg) + Vitamin B6 (Pyridoxine) (50mg) + Nicotinamide (50mg) + D-Panthenol (25mg). It belongs to the B-complex vitamin and Moisturiser / skin barrier repair class of medicines.
Nutritional deficiencies
Bethadoxin 12 Injection is a combination of five nutritional supplements: Methylcobalamin, Thiamine(Vitamin B1), Vitamin B6 (Pyridoxine), Nicotinamide and D-Panthenol which replenish the body's stores of important nutrients.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Bethadoxin 12 Injection, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It is not a realistic risk from a moisturiser used on the skin. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Bethadoxin-12 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding SAFE IF PRESCRIBED |
| Alcohol | Alcohol CAUTION |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney SAFE IF PRESCRIBED |
| Liver | Liver SAFE IF PRESCRIBED |
| Habit forming | No |
Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. Apply generously and often — several times a day, and always within a few minutes of a bath while the skin is still damp. Some paraffin-based emollients are flammable when they soak into clothing and bedding. Keep away from open flames and cigarettes. Stop if the skin becomes more red, itchy or sore after use.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. No significant interactions are expected.
Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.
Bethadoxin 12 Injection is prescribed to fulfill your nutritional requirement and to prevent any related diseases. Avoid taking antacids 2 hours before or after taking Bethadoxin 12 Injection as they make it harder for your body to absorb the medicine. Let your doctor know if you are taking any other medications like for bone disorders, antihypertensives, antibiotics, or medicines for heart disease.

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The information on Bethadoxin-12 Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.