
Amrfy Cream
H & H Pharmaceutical Pvt Ltd - Cream - 30 G
Prescription required
Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w (topical gel)
Cleargel Nico Gel is used for acne vulgaris (inflammatory acne), pimples with redness and swelling; helps in acne marks and oily skin control as supportive care.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Cleargel Nico Gel contains Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w (topical gel). It belongs to the Topical antibiotic + Vitamin B3 derivative (anti-inflammatory) class of medicines.
Clindamycin inhibits bacterial protein synthesis and reduces Cutibacterium acnes, decreasing inflammation. Nicotinamide has anti-inflammatory effects and may reduce sebum and improve skin barrier, helping reduce redness and acne lesions.
External use only. Apply a thin layer to clean, dry affected skin once or twice daily as advised; avoid eyes, mouth and mucosa; use moisturizer/sunscreen if dryness or sensitivity occurs.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Cleargel Nico are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | No known interaction |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Discontinue if severe irritation or persistent diarrhea occurs. Avoid overuse and combining with multiple irritant acne products unless advised. Use caution in sensitive skin, eczema, or history of colitis.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Other topical acne agents (retinoids, benzoyl peroxide, salicylic acid) may increase irritation; topical erythromycin may reduce effectiveness of clindamycin
Store below 25-30°C, away from direct sunlight and heat; keep tightly closed.
Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.
Medicines with the same active ingredient (Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w (topical gel)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Cleargel Nico Gel |
|---|---|---|---|
| Acnovate GelAPEX LABORATORIES LTD` | gel · 15GM | ₹327 | 79% more |

H & H Pharmaceutical Pvt Ltd - Cream - 30 G
Prescription required

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Prescription required

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Prescription required
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Life Gain Pharma - Tablet - 10 S
Prescription required
Med Manor Organics Pvt Ltd - Gel - 10 G
Prescription required
Zydus Healthcare Pharma - Tablet - 625 mg - 10 S
Prescription required

Genfo Bioceuticals Pvt Ltd - Tablet - 10 S
Prescription required
Cipla Limited - 10 S
Prescription required

Empee Distributors - Cream - 30 gm - 30 G
Prescription required
Medopharm - 10
Prescription required

Sun Pharma 2 - Tablet - 300 mg - 10 S
Prescription required

Icon Pharma - 10 mg - 10 S
Prescription required

East West Pharma - Tablet - 10 mg - 10 S
Prescription required
Glenmark Pharmaceuticals - Tablet - 5 mg - 10 S
Prescription required

Micro Labs - Cream - 15 gm - 15 G
Prescription required

Micro Labs - Capsule - 10 S
Prescription required
Walter Bushnel - 10 mg - 10 S
Prescription required

Brinton Pharmaceuticals Pvt Ltd - Cream - 15 G
Prescription required

Abbott Healthcare Pvt Ltd - Vial - 40 mg - Vial
Prescription required
The information on Cleargel Nico Gel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.