Dapazep M 10/500 Tablet

Composition of Dapazep M 10/500 Tablet

Dapazep M 10/500 Tablet contains Dapagliflozin 10 mg + Metformin 500 mg (as Metformin Hydrochloride). It belongs to the SGLT2 inhibitor + Biguanide class of medicines.

Uses of Dapazep M 10/500 Tablet

Type 2 diabetes mellitus (to improve glycaemic control) along with diet and exercise; may be used when metformin alone is inadequate

Key benefits

• Lowers blood glucose in type 2 diabetes
• Improves insulin sensitivity and reduces hepatic glucose output
• Promotes urinary glucose excretion
• May aid modest weight reduction
• Lowers risk of hypoglycaemia when not used with insulin/secretagogues

How Dapazep M 10/500 Tablet works

Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion. Metformin decreases hepatic glucose production and improves insulin sensitivity, helping lower blood glucose.

How to take Dapazep M 10/500 Tablet

Oral tablet. Take exactly as prescribed. Metformin-containing tablets are usually taken with meals to reduce stomach upset. Maintain adequate hydration; do not crush/chew unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Dapazep M 10/500 as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Dapazep M 10/500 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Dapazep M 10/500 Tablet

Most side effects of Dapazep M 10/500 are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• diarrhoea
• abdominal discomfort
• decreased appetite
• headache
• increased urination
• genital fungal infection
• urinary tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dapazep M 10/500 Tablet

Warnings and precautions

Prescription medicine. Risk of lactic acidosis with metformin (higher risk in kidney impairment, dehydration, severe infection, alcohol misuse); kidney function should be assessed before and during therapy. Dapagliflozin may cause dehydration/low blood pressure and genital mycotic infections; rarely ketoacidosis can occur even with near-normal glucose—seek urgent care for nausea, vomiting, abdominal pain, rapid breathing. Temporarily stop during major surgery or severe illness and before iodinated contrast as advised by doctor. Use caution in elderly and those on diuretics. Not for type 1 diabetes.

Interactions with other medicines

Diuretics (increased dehydration/hypotension), insulin/sulfonylureas (increased hypoglycaemia risk), ACE inhibitors/ARBs (may increase risk of low BP with SGLT2), iodinated contrast media (increased lactic acidosis risk—metformin may need to be withheld), alcohol (increases lactic acidosis risk), cationic drugs affecting renal tubular secretion e.g., cimetidine (may increase metformin levels)

How to store Dapazep M 10/500 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Manufacturer and class

Manufacturer:

ERGOS LIFE SCIENCES

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + Biguanide