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Prescription requiredKlm LabDermatological (Emollient/Moisturiser)

Desosoft Cream

Desonide (0.05%w/w)

₹134MRP ₹141In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Desosoft Cream is used for moisturiser/skin barrier repair cream used for dry skin (xerosis), rough/scaly skin, and supportive care in eczema/dermatitis where emollients are advised.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Desonide (0.05%w/w)
Available variants: cream 0.05%w/w 10GM
Best price: ₹134 (₹13.36 per g)
MRP: ₹141
Prescription: Required
Manufacturer: KLM LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

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Desosoft Cream

cream - 0.05%w/w - 10 g

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₹13.36 per g

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Desosoft Cream. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Desosoft Cream

Desosoft Cream contains Desonide (0.05%w/w). It belongs to the Topical emollient (skin protectant) class of medicines.

Uses of Desosoft Cream

  • Moisturiser/skin barrier repair cream used for dry skin (xerosis)
  • rough/scaly skin
  • and supportive care in eczema/dermatitis where emollients are advised.

Key benefits

  • Moisturises very dry skin
  • Reduces roughness and scaling
  • Supports skin barrier
  • Helps relieve itching due to dryness
  • Useful as adjunct in eczema care

How Desosoft Cream works

Acts as an emollient that hydrates the stratum corneum and reduces transepidermal water loss. By softening and smoothing the skin and supporting the barrier, it helps relieve dryness and irritation.

How to take Desosoft Cream

For external use only. Apply a thin layer to clean, dry affected area 1-3 times daily or as directed by a doctor. Use regularly; avoid contact with eyes and broken/infected skin unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Desosoft Cream

Most side effects of Desosoft are mild and settle as the body adjusts. Reported side effects include:

  • Mild burning
  • stinging
  • redness
  • itching
  • irritation
  • rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Desosoft Cream

PregnancyGenerally safe (topical emollient); consult doctor if extensive use is planned
BreastfeedingDesosoft Cream is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
AlcoholNo known interaction
DrivingNot expected to affect your ability to drive.
KidneyNo interaction found/established
LiverNo interaction found/established
Habit formingNo

Warnings and precautions

Stop use and consult a doctor if severe irritation, swelling, or allergic reaction occurs. Do not apply on deep/open wounds unless advised. If used in children, during pregnancy, or on large areas for long durations, consult a healthcare professional. Keep away from eyes; rinse with water if accidental contact occurs.

Do not take Desosoft if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

No known clinically significant drug interactions when used as a topical moisturiser; if using other topical medicines, apply at different times or as advised to avoid dilution.

How to store Desosoft Cream

Store at room temperature (below 25°C), away from heat and direct light. Keep the cap tightly closed and protect from moisture. Keep out of reach of children.

Expert advice for Desosoft Cream

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Desosoft Cream is used to treat the redness, swelling, itching, and discomfort of various skin conditions.</li> <li>It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.</li> <li>Don't use it more often or for longer than advised by your doctor.</li> <li>Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.</li> <li>If you think the area of skin you are treating has become infected you should stop using Desosoft Cream and consult your doctor.</li> <li>Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.</li> <li>Side effects such as mood changes or stomach problems can happen when you start taking Desosoft Cream . Inform your doctor if this bothers you.</li> <li>Do not stop taking Desosoft Cream suddenly without talking to your doctor first as it may cause worsening of symptoms.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
KLM LAB
Therapeutic class:
Dermatological (Emollient/Moisturiser)
Drug class:
Topical emollient (skin protectant)

Substitutes for Desosoft Cream

Medicines with the same active ingredient (Desonide (0.05%w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Desosoft Cream
Desoadd LotionIntas Pharmaceuticals Ltdlotion · 30ML₹15617% more
Atonide GelTorrent Pharmaceuticals Ltdgel · 20GM₹15919% more
Desoadd CreamIntas Pharmaceuticals Ltdcream · 15G₹17128% more
Cliodes CreamTRODAN & CLAIES HEALTHCAREcream · 20GM₹17430% more
Desonfin Cream24C DERMA LABScream · 20GM₹19646% more
Atonide CreamTorrent Pharmaceuticals Ltdcream · 20GM₹24785% more
Desowen LotionGALDERMA INDIA PVT LTDlotion · 30ML₹276107% more
Desowen CreamGALDERMA INDIA PVT LTDcream · 10GM₹276107% more
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Desosoft Cream FAQs

What is Desosoft Cream used for?
Desosoft Cream is commonly used for Moisturiser/skin barrier repair cream used for dry skin (xerosis), rough/scaly skin, and supportive care in eczema/dermatitis where emollients are advised. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Desosoft Cream?
Desosoft Cream contains Desonide (0.05%w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Desosoft Cream?
For external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Desosoft Cream work?
Acts as an emollient that hydrates the stratum corneum and reduces transepidermal water loss.
Is Desosoft Cream a prescription medicine?
Yes. Desosoft Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Desosoft Cream?
The side effects reported most often with Desosoft are Mild burning, stinging, redness, itching, irritation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Desosoft Cream be taken during pregnancy?
Generally safe (topical emollient); consult doctor if extensive use is planned Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Desosoft.
Can I drink alcohol while taking Desosoft Cream?
No known interaction
What if I miss a dose of Desosoft Cream?
Apply it as soon as you remember.
Is Desosoft Cream habit forming?
No. Desosoft Cream is not known to be habit forming when taken as prescribed.
How much does Desosoft Cream cost on PingMeDoc Pharmacy?
Desosoft Cream starts at ₹134 (MRP ₹141) on PingMeDoc Pharmacy. Available in cream 0.05%w/w 10GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Desosoft Cream?
Desosoft Cream is manufactured by KLM LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Desosoft Cream delivered?
Desosoft Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Desosoft Cream, Quick facts

Salt
Desonide (0.05%w/w)
Form
cream
Best price
₹134 (₹13.36 per g)
MRP
₹141
Prescription
Required (Rx)
Brand
KLM LAB
Manufacturer
KLM LAB
Therapeutic class
Dermatological (Emollient/Moisturiser)
Drug class
Topical emollient (skin protectant)
Habit forming
No
Variants
cream 0.05%w/w 10GM
Delivery
Standard across India

References

The information on Desosoft Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack information, established dermatology literature on emollients, standard pharmacy/dermatology references
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Desosoft Cream.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.