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Comed Chemicals - Tablet - 15 S
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Betamethasone + Zinc sulphate
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This medicine needs a prescription.
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Diprobate G Plus Cream is used for this medicine is used in the treatment of inflammation, allergic reactions, autoimmune conditions, asthma flare, nutritional deficiency, support during recovery and antioxidant supplementation.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Diprobate G Plus Cream contains Betamethasone + Zinc sulphate. It belongs to the Systemic corticosteroid and Antioxidant / trace element supplement class of medicines.
This medicine combines 2 active ingredients: Betamethasone and Zinc Sulphate. Betamethasone suppresses inflammation and calms an over-active immune response throughout the body. Zinc Sulphate supplies a nutrient that helps protect body cells from everyday oxidative wear and supports normal immune function.
Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. It can cause vomiting, stomach pain and, with some minerals, damage over the longer term. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Diprobate G Plus are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Never stop a course of more than a few days suddenly. Your body stops making its own steroid while you take these, and abrupt withdrawal can cause a dangerous collapse. Your doctor will taper the dose. Tell any doctor treating you that you take steroids, and say so urgently if you develop a serious infection, injury or need surgery — you may need a higher dose to cope. Steroids raise blood sugar. If you have diabetes, monitor it more closely during a course. Long-term use thins bones, raises the risk of infection, cataract and glaucoma. Your doctor will monitor and may add bone protection. Chickenpox and measles can be severe in people on steroids — seek advice promptly after any contact. A supplement supports a normal diet; it does not prevent or treat infection. Zinc on an empty stomach commonly causes nausea — take it with food. Very high doses of vitamin A over a long period can be harmful, particularly in pregnancy. Do not take several products containing the same nutrient at once; the totals add up.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated systemic infection, except where the steroid is part of the treatment.
Anti-inflammatory painkillers together with steroids markedly raise the risk of stomach bleeding. Live vaccines are generally avoided during significant steroid treatment. Zinc and other minerals reduce the absorption of some antibiotics — separate them by a few hours. Tell your doctor if you take a blood thinner, as high-dose vitamin E can add to its effect.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Take the whole daily dose in the morning with food, unless your doctor directs otherwise — this suits the body's own rhythm and helps you sleep. Carry a steroid card or note if you are on a long course. Watch your salt, sugar and weight during the course. Take it with food to reduce nausea. A varied diet remains the best source of these nutrients.

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The information on Diprobate G Plus Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.