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Prescription requiredCorticosteroid and Nutritional supplement
Diprobate Plus Cream
Betamethasone (0.05%w/w) + Zinc Sulphate (0.5%w/w)
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Diprobate Plus Cream is used for diprobate Plus Cream is used in the treatment of dermatitis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Betamethasone (0.05%w/w) + Zinc Sulphate (0.5%w/w)
Available variants: cream 30 Gm
Best price: ₹81 (₹2.70 per g)
MRP: ₹90
Prescription: Required
Manufacturer: Sun Pharma Laboratories Ltd
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Diprobate Plus Cream
Diprobate Plus Cream contains Betamethasone (0.05%w/w) + Zinc Sulphate (0.5%w/w). It belongs to the Systemic corticosteroid and Antioxidant / trace element supplement class of medicines.
Uses of Diprobate Plus Cream
Diprobate Plus Cream is used in the treatment of dermatitis.
Key benefits
- Fast and powerful control of inflammation
- Life-saving in severe allergic and autoimmune disease
- Corrects dietary shortfalls
- Supports normal immune function
How Diprobate Plus Cream works
Diprobate Plus Cream is a combination of two medicines: Betamethasone and Zinc Sulfate. Betamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Zinc Sulfate works as an astringent and antiseptic on the skin.
How to take Diprobate Plus Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
If you take too much
An overdose of this medicine can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. It can cause vomiting, stomach pain and, with some minerals, damage over the longer term. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Diprobate Plus Cream
Most side effects of Diprobate Plus are mild and settle as the body adjusts. Reported side effects include:
- Application site reactions (burning
- irritation
- itching and redness)
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Diprobate Plus Cream
| Pregnancy | Diprobate Plus Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Diprobate Plus Cream is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | No interaction found/established |
| Driving | Not expected to affect your ability to drive. |
| Kidney | No interaction found/established |
| Liver | No interaction found/established |
| Habit forming | No |
Warnings and precautions
Never stop a course of more than a few days suddenly. Your body stops making its own steroid while you take these, and abrupt withdrawal can cause a dangerous collapse. Your doctor will taper the dose. Tell any doctor treating you that you take steroids, and say so urgently if you develop a serious infection, injury or need surgery — you may need a higher dose to cope. Steroids raise blood sugar. If you have diabetes, monitor it more closely during a course. Long-term use thins bones, raises the risk of infection, cataract and glaucoma. Your doctor will monitor and may add bone protection. Chickenpox and measles can be severe in people on steroids — seek advice promptly after any contact. A supplement supports a normal diet; it does not prevent or treat infection. Zinc on an empty stomach commonly causes nausea — take it with food. Very high doses of vitamin A over a long period can be harmful, particularly in pregnancy. Do not take several products containing the same nutrient at once; the totals add up.
Do not take Diprobate Plus if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated systemic infection, except where the steroid is part of the treatment.
Interactions with other medicines
Anti-inflammatory painkillers together with steroids markedly raise the risk of stomach bleeding. Live vaccines are generally avoided during significant steroid treatment. Zinc and other minerals reduce the absorption of some antibiotics — separate them by a few hours. Tell your doctor if you take a blood thinner, as high-dose vitamin E can add to its effect.
How to store Diprobate Plus Cream
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Expert advice for Diprobate Plus Cream
Take the whole daily dose in the morning with food, unless your doctor directs otherwise — this suits the body's own rhythm and helps you sleep. Carry a steroid card or note if you are on a long course. Watch your salt, sugar and weight during the course. Take it with food to reduce nausea. A varied diet remains the best source of these nutrients.
Manufacturer and class
- Manufacturer:
- Sun Pharma Laboratories Ltd
- Therapeutic class:
- Corticosteroid and Nutritional supplement
- Drug class:
- Systemic corticosteroid and Antioxidant / trace element supplement
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Diprobate Plus Cream FAQs
What is Diprobate Plus Cream used for?
Diprobate Plus Cream is commonly used for Diprobate Plus Cream is used in the treatment of dermatitis. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Diprobate Plus Cream?
Diprobate Plus Cream contains Betamethasone (0.05%w/w) + Zinc Sulphate (0.5%w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Diprobate Plus Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Diprobate Plus Cream work?
Diprobate Plus Cream is a combination of two medicines: Betamethasone and Zinc Sulfate.
Is Diprobate Plus Cream a prescription medicine?
Yes. Diprobate Plus Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Diprobate Plus Cream?
The side effects reported most often with Diprobate Plus are Application site reactions (burning, irritation, itching and redness). Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Diprobate Plus Cream be taken during pregnancy?
Diprobate Plus Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Diprobate Plus.
Can I drink alcohol while taking Diprobate Plus Cream?
No interaction found/established
What if I miss a dose of Diprobate Plus Cream?
Apply it as soon as you remember.
Is Diprobate Plus Cream habit forming?
No. Diprobate Plus Cream is not known to be habit forming when taken as prescribed.
How much does Diprobate Plus Cream cost on PingMeDoc Pharmacy?
Diprobate Plus Cream starts at ₹81 (MRP ₹90) on PingMeDoc Pharmacy. Available in cream 30 Gm. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Diprobate Plus Cream?
Diprobate Plus Cream is manufactured by Sun Pharma Laboratories Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Diprobate Plus Cream delivered?
Diprobate Plus Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Diprobate Plus Cream, Quick facts
- Salt
- Betamethasone (0.05%w/w) + Zinc Sulphate (0.5%w/w)
- Form
- cream
- Best price
- ₹81 (₹2.70 per g)
- MRP
- ₹90
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Manufacturer
- Sun Pharma Laboratories Ltd
- Therapeutic class
- Corticosteroid and Nutritional supplement
- Drug class
- Systemic corticosteroid and Antioxidant / trace element supplement
- Habit forming
- No
- Variants
- cream 30 Gm
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Diprobate Plus Cream.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.