
Aceclo 100MG
Aristo Pharmaceuticals Pvt Ltd - 100 mg - 10 S
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Epalrestat (150mg) + Methylcobalamin (1500mcg)
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Epineuron SR Tablet is used for diabetic nerve pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Epineuron SR Tablet contains Epalrestat (150mg) + Methylcobalamin (1500mcg). It belongs to the Oral anti-diabetic and B-complex vitamin class of medicines.
Diabetic nerve pain
Epineuron SR Tablet is a combination of two medicines:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epineuron SR Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Epineuron SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine may cause low blood sugar and marked stomach upset. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Epineuron SR are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol CAUTION |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Low blood sugar is more likely when combined with insulin or a sulfonylurea. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it only as per the dose and duration prescribed by your doctor. Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease. Inform your doctor if you have: Cut or sore on your feet that is infectious or not healing Burning or tingling sensation in arm or feet that hamper your routine activities Trouble in digestion, urination, or sexual functioning Dizziness To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early. Monitor your blood sugar level regularly. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

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The information on Epineuron SR Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.