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Prescription requiredIcon PharmaANTI DIABETIC

Glemine 1

Glimepiride (2mg) + Metformin (500mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Linpride-2₹44View
  • Glidum-Mf2₹49View
  • Glimed Mf2 Tablet₹49View

Glemine 1 is used for treatment of Type 2 diabetes mellitus Hormone replacement therapy.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Glimepiride (2mg) + Metformin (500mg)
Available variants: NA 10`S
Best price: ₹51
MRP: ₹53
Prescription: Required
Manufacturer: ICON PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Glemine 1

Glemine 1 contains Glimepiride (2mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Glemine 1

Treatment of Type 2 diabetes mellitus Hormone replacement therapy

Key benefits

  • In Treatment of Type 2 diabetes mellitus Glemine 2 Tablet SR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level
  • you will reduce the risk of getting any of the serious complications of diabetes
  • such as kidney damage
  • eye damage
  • nerve problems
  • and loss of limbs. Taking this medicine regularly
  • along with proper diet and exercise
  • will help you live a normal
  • healthy life. In Hormone replacement therapy In patients already controlled on separate treatment with glimepiride and metformin
  • this combination may be used as a replacement to simplify treatment while maintaining blood sugar control. It is indicated in adults 18 years and older. Show More

How Glemine 1 works

Glemine 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

How to take Glemine 1

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glemine 2 Tablet SR should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Glemine 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glemine 1

Most side effects of Glemine are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glemine 1

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving CAUTION
KidneyKidney UNSAFE
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Glemine if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Glemine 1

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Glemine 1

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glemine 2 Tablet SR. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glemine 2 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:
ICON PHARMA
Therapeutic class:
ANTI DIABETIC
Drug class:
Sulfonylurea and Biguanide

Substitutes for Glemine 1

Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Glemine 1
Linpride-2BALINT PHARMA10`S₹4413% cheaper
Glidum-Mf21X10₹493% cheaper
Glimed Mf2 Tablet1X10₹493% cheaper
Ozomet G2 TabletOZONE PHARMACEUTICALS LTDtablet · 15`S₹5713% more
Glucobeat G2 TabletSAAN LAB LLPtablet · 10`S₹5814% more
Glucobeat G2 Forte TabletSAAN LAB LLPtablet · 10`S₹6121% more
Gala-MG 1 TabletKINESIS PHARMACEUTICALS (P) LTD.`tablet · 10`S₹9791% more
Humiglim 2 mg TabletVERSE LIFESCIENCEStablet · 30`S₹114125% more
Diapride M 1MICRO LABS15`S₹152199% more
Glimp M2 TabletCOMMON PRODUCTStablet · 10`S₹156207% more
Glimestar-M2 TabletMANKIND (PHARMA)tablet · 15`S₹169233% more
Aristomet G2 Tablet1X15₹181256% more
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Glemine 1 FAQs

What is Glemine 1 used for?
Glemine 1 is commonly used for Treatment of Type 2 diabetes mellitus Hormone replacement therapy. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Glemine 1?
Glemine 1 contains Glimepiride (2mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Glemine 1?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Glemine 1 work?
Glemine 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin.
Is Glemine 1 a prescription medicine?
Yes. Glemine 1 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Glemine 1?
The side effects reported most often with Glemine are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Glemine 1 be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Glemine.
Can I drink alcohol while taking Glemine 1?
Alcohol UNSAFE
What if I miss a dose of Glemine 1?
If you miss a dose of Glemine 2 Tablet SR, take it as soon as possible.
Is Glemine 1 habit forming?
No. Glemine 1 is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Glemine 1?
Linpride-2 has the same active ingredient and strength and is listed from ₹44 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Glemine 1 cost on PingMeDoc Pharmacy?
Glemine 1 starts at ₹51 (MRP ₹53) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Glemine 1?
Glemine 1 is manufactured by ICON PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Glemine 1 delivered?
Glemine 1 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Glemine 1, Quick facts

Salt
Glimepiride (2mg) + Metformin (500mg)
Best price
₹51
MRP
₹53
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ICON PHARMA
Manufacturer
ICON PHARMA
Therapeutic class
ANTI DIABETIC
Drug class
Sulfonylurea and Biguanide
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Glemine 1.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.