
Akilos-P Tab
UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery
Distributor inventory | Tablet
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Glimepiride 1 mg + Metformin hydrochloride (sustained/extended release) 500 mg + Pioglitazone 15 mg
Type 2 diabetes mellitus (in adults) when blood sugar is not adequately controlled with diet, exercise and single/dual oral antidiabetic therapy
Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin reduces glucose production in the liver and improves insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and fat by activating PPAR-γ, helping reduce blood glucose.
Oral tablet; take exactly as prescribed. Usually taken once daily with the first main meal (or as directed). Swallow whole (do not crush/chew if SR/ER); take with food to reduce stomach upset. Monitor blood glucose regularly.
Common side effects of Glimison Mp 1 Tab may include:

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery
UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 mg - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery

UNISON PHARMACEUTICALS - tablet - 10 S
Standard delivery
Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise); carry glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, dehydration, severe infection, alcoholism, heart/respiratory failure; stop and seek care for rapid breathing, severe weakness, abdominal pain. Pioglitazone can cause fluid retention/worsen heart failure; avoid in NYHA class III/IV and use caution in cardiac disease; monitor for weight gain/edema. Monitor kidney function and liver enzymes; stop if jaundice or significant LFT elevation. Long-term metformin may reduce vitamin B12—consider periodic monitoring. Use caution in elderly and in those with renal/hepatic impairment. Temporarily stop metformin around iodinated contrast/surgery as advised by doctor.