Glycomet 500 Tablet

Composition of Glycomet 500 Tablet

Glycomet 500 Tablet contains Metformin (500mg). It belongs to the Biguanide class of medicines.

Uses of Glycomet 500 Tablet

• Type 2 diabetes mellitus (to control blood glucose)
• Prediabetes/insulin resistance (as advised by doctor)
• Polycystic ovary syndrome (PCOS) with insulin resistance (off-label
• as prescribed)

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity
• Helps reduce diabetes-related complications with good control
• Weight-neutral or modest weight loss in many patients
• Can improve menstrual regularity in PCOS (when prescribed)

How Glycomet 500 Tablet works

Metformin decreases glucose production in the liver and reduces intestinal glucose absorption. It also improves insulin sensitivity in muscle and fat, helping the body use insulin better and lowering blood sugar without usually causing hypoglycaemia when used alone.

How to take Glycomet 500 Tablet

Tablet (immediate-release): take exactly as prescribed, usually with or after meals to reduce stomach upset. Swallow with water; do not crush unless advised. Take at the same time each day; if a dose is missed, take it when remembered unless it is close to the next dose (do not double).

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Glycomet 500 SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glycomet 500 Tablet

Most side effects of Glycomet are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• metallic taste
• flatulence
• headache
• vitamin B12 deficiency (with long-term use)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glycomet 500 Tablet

Warnings and precautions

Risk of lactic acidosis (rare but serious) especially with kidney disease, severe dehydration, sepsis, shock, severe liver disease, or heavy alcohol use—seek urgent care for rapid breathing, severe weakness, persistent vomiting, abdominal pain or drowsiness. Use with caution in renal impairment; kidney function should be checked before and during therapy. Temporarily stop metformin during severe vomiting/diarrhoea/dehydration and before/after iodinated contrast procedures or major surgery as advised by doctor. Monitor for hypoglycaemia when combined with insulin or sulfonylureas. Long-term use may lower vitamin B12—periodic monitoring may be needed.

Do not take Glycomet if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol, Iodinated contrast media, Insulin and sulfonylureas (e.g., glimepiride) (increased hypoglycaemia risk), Cimetidine (may increase metformin levels), Carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide) (increased acidosis risk), Diuretics and ACE inhibitors/ARBs (via dehydration/renal function changes), Corticosteroids and some antipsychotics (may raise blood glucose)

How to store Glycomet 500 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Glycomet 500 Tablet

The chances of weight gain and low blood sugar are lower with this medicine as compared to other diabetes medicines. Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines or alcohol, or on delaying/skipping a meal. Carry a sugar source with you for immediate relief. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Glycomet 500 SR Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Prolonged use of Glycomet 500 SR Tablet may lead to vitamin B12 deficiency, which may lead to anemia, causing fatigue, pale skin, shortness of breath, or headache. Notify your doctor if you experience any of these, as you may require supplements. Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication.

Manufacturer and class

Manufacturer:

USV LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Biguanide

Chemical class:

Biguanide derivative