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Biocon Ltd - Drop - 15 ml
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Human insulin (recombinant) Injection IP 100 IU/mL (Regular insulin)
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Insugen N Refil 3 ml is used for treatment of diabetes mellitus (Type 1 and Type 2) to control high blood glucose; may be used in diabetic ketoacidosis or peri-operative/acute illness settings as advised by doctor.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Insugen N Refil 3 ml contains Human insulin (recombinant) Injection IP 100 IU/mL (Regular insulin). It belongs to the Insulin (short-acting human insulin/regular insulin) class of medicines.
Treatment of diabetes mellitus (Type 1 and Type 2) to control high blood glucose; may be used in diabetic ketoacidosis or peri-operative/acute illness settings as advised by doctor
Regular human insulin replaces/supplements natural insulin. It helps glucose enter muscle and fat cells and reduces glucose production by the liver, thereby lowering blood sugar levels.
For subcutaneous injection using compatible insulin pen/cartridge system as prescribed. Usually injected about 30 minutes before meals; dose and timing individualized based on blood glucose. Do not share pens/needles; rotate injection sites (abdomen, thigh, upper arm). Use only if solution is clear and colorless; follow doctor’s instructions for mixing if used with other insulins.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Contact your doctor or diabetes nurse for advice — do not take a double dose to make up for a missed injection.
An overdose of this medicine can cause severe low blood sugar, leading to fits or unconsciousness — this is a medical emergency. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Insugen N Refil are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor (generally safe when prescribed; insulin is preferred for diabetes control in pregnancy, dose adjustments needed) |
|---|---|
| Breastfeeding | Generally considered safe while breastfeeding. |
| Alcohol | Use with caution (may cause hypoglycaemia) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Risk of hypoglycaemia—monitor blood glucose and know symptoms (sweating, tremor, hunger, confusion). Dose adjustments may be needed with changes in diet, activity, illness, stress, kidney/liver impairment. Do not use during episodes of hypoglycaemia or if allergic to insulin/excipients. Use caution when driving/operating machinery due to hypoglycaemia risk. Ensure correct insulin type/strength and cartridge compatibility; do not use if frozen, cloudy, or discoloured.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not to be used during an episode of low blood sugar.
Other antidiabetics, ACE inhibitors/ARBs, salicylates, MAO inhibitors can increase hypoglycaemic effect; corticosteroids, thiazide/loop diuretics, thyroid hormones, oral contraceptives, sympathomimetics can raise blood glucose and reduce insulin effect; beta-blockers may mask hypoglycaemia symptoms; alcohol can increase risk of hypoglycaemia; pioglitazone with insulin may increase risk of fluid retention/heart failure
Store refrigerated at 2–8°C; do not freeze. Keep away from light and heat; keep cartridge in outer carton. If in use, follow pen/cartridge instructions; generally can be kept at room temperature below 25–30°C for a limited period as per pack insert; discard if frozen or after recommended in-use period.
Keep an unopened supply in the fridge and the pen in use at room temperature, away from direct sunlight. Always carry a fast-acting sugar source. Check your sugar as your doctor has instructed, and keep a record to take to appointments.
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The information on Insugen N Refil 3 ml is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.