
Apduo Tabs
Dee Gradibus Life Care (P) Ltd - Tablet - 10mg - 10 S
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
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L-Fame Plus Tablet is used for used as a nutritional/haematinic supplement to support red blood cell formation and nerve health; commonly used in folate or vitamin B12 deficiency, megaloblastic anemia, and as an adjunct in pregnancy-related supplementation when prescribed.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Products named with “L-FAME” are typically formulations containing L-methylfolate (active folate) with supportive vitamins. L-methylfolate helps in DNA synthesis and red blood cell formation, while vitamin B12 (if present) supports nerve function and works with folate in homocysteine metabolism.
Take orally as directed by the physician, usually once daily. Can be taken with or without food; taking after food may reduce stomach upset. Swallow the tablet whole with water.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of L-Fame Plus as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more L-Fame Plus than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of L-Fame Plus are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Alcohol | Use with caution |
| Habit forming | No |
Do not self-medicate for anemia without evaluation (iron, B12, folate deficiency need confirmation). Use with caution in patients with history of hypersensitivity to B-vitamins/folate products. High-dose folate can mask vitamin B12 deficiency and allow neurological damage to progress—ensure B12 status is assessed when indicated. Patients with seizure disorders on antiepileptics should consult a doctor.
Antiepileptics (phenytoin, phenobarbital, primidone), methotrexate (dose-dependent; folate may reduce toxicity), trimethoprim/pyrimethamine, sulfasalazine, chloramphenicol (may blunt hematologic response), metformin and PPIs (can reduce vitamin B12 levels if present in regimen)
Store at room temperature (below 25°C), protected from light and moisture. Keep in original pack and out of reach of children.

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The information on L-Fame Plus Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.