Advog 0.3
Eris Life Sciences Pvt Ltd - 10 S
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Empagliflozin (10mg) + Linagliptin (5mg) + Metformin (1000mg)
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Linares Trio 10/5/1000 mg Tablet is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Linares Trio 10/5/1000 mg Tablet contains Empagliflozin (10mg) + Linagliptin (5mg) + Metformin (1000mg). It belongs to the SGLT2 inhibitor / GLP-1 analogue, DPP-4 inhibitor and Biguanide class of medicines.
Treatment of Type 2 diabetes mellitus
LinARES Trio 10/5/1000 Tablet ER is a combination of three medicines: empagliflozin, linagliptin, and metformin hydrochloride. Empagliflozin works by blocking a protein in the kidneys called SGLT2 (sodium-glucose cotransporter 2), which normally reabsorbs sugar back into the blood. Empagliflozin blocks this protein, allowing more sugar to be removed from the body through urine. Linagliptin inhibits the enzyme DPP-4 (dipeptidyl peptidase-4), which rapidly breaks down incretin hormones like GLP-1 and GIP that stimulate insulin release from the pancreas and suppress glucagon in a glucose-dependent manner, thereby helping to lower blood sugar levels after meals. Metformin hydrochloride reduces the amount of sugar produced by the liver and helps the body respond better to insulin. Together, they control blood sugar through multiple ways, leading to more stable glucose levels and reduced risk of complications related to type 2 diabetes.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. LinARES Trio 10/5/1000 Tablet ER should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of LinARES Trio 10/5/1000 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause dehydration and a fall in blood pressure. It may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Linares Trio 10/5/1000 mg are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CAUTION |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take LinARES Trio 10/5/1000 Tablet ER at the same time each day. Set a daily reminder or alarm to avoid missing doses. Call your doctor if you feel very weak, confused, or have trouble breathing while taking LinARES Trio 10/5/1000 Tablet ER. These may be signs of serious side effects needing urgent care. Drink enough fluids daily unless your doctor advises otherwise. Aim for at least 6–8 glasses of water a day to prevent dehydration. Inform your doctor before any planned surgeries or contrast imaging tests. You may need to stop LinARES Trio 10/5/1000 Tablet ER temporarily to prevent kidney problems. Carry a source of fast-acting sugar like glucose tablets or candy. Use it immediately if you feel dizzy, sweaty, shaky, or confused.
Medicines with the same active ingredient (Empagliflozin (10mg) + Linagliptin (5mg) + Metformin (1000mg)). Ask your doctor or pharmacist before switching brands.
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The information on Linares Trio 10/5/1000 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.