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Zuventus Healthcare Ltd - Capsule - 10 S
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Nicotinamide (20mg/5ml) + L-Ornithine L-Aspartate (250mg/5ml)
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Lornit I.V Vial is used for adjunct in liver disorders associated with raised ammonia levels such as hepatic encephalopathy, fatty liver and other hepatic dysfunction; used to support liver detoxification and improve symptoms like confusion, fatigue and poor appetite in liver disease (as advised by doctor).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Lornit I.V Vial contains Nicotinamide (20mg/5ml) + L-Ornithine L-Aspartate (250mg/5ml). It belongs to the Ammonia-lowering agent (L-ornithine L-aspartate) + Vitamin (Nicotinamide) class of medicines.
L-ornithine L-aspartate provides substrates that enhance the urea cycle and glutamine synthesis in the liver, helping convert toxic ammonia into urea/glutamine for elimination. Nicotinamide supports energy metabolism and nutritional replenishment, often needed in chronic liver disease.
I.V. vial: to be administered only by a healthcare professional as slow IV injection/infusion after dilution as prescribed. Dose and duration depend on indication and ammonia levels; do not self-administer. May be used in hospital/clinic settings; follow doctor’s instructions.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It may cause loose motions and stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Lornit I.V Vial are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
For intravenous use only; administer under medical supervision. Use with caution in severe renal impairment and monitor kidney function. Hypersensitivity reactions may occur—stop infusion and seek medical help if rash, swelling, breathing difficulty occurs. Monitor ammonia levels and clinical status in hepatic encephalopathy. Not a substitute for definitive management of liver failure; avoid self-medication.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
No major interactions commonly reported for L-ornithine L-aspartate; however, inform doctor about all medicines. Nicotinamide may affect glycaemic control (antidiabetics), and high doses may interact with hepatotoxic drugs; monitor if used with other liver-impacting medicines.
Store below 25°C. Protect from light. Do not freeze. Keep in original carton; use immediately after opening/dilution as per hospital protocol.
A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for. Avoid alcohol entirely, and avoid unnecessary medicines and unregulated herbal preparations. Weight loss and exercise are the proven treatment for fatty liver.
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The information on Lornit I.V Vial is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.