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Prescription requiredLupin LabVitamin supplement and Neuropathic pain agent

Matilda ER

Methylcobalamin (1500mcg) + Pregabalin (75mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹348

Matilda ER is used for matilda PG ER Tablet is used in the treatment of neuropathic pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Methylcobalamin (1500mcg) + Pregabalin (75mg)
Available variants: NA 10`S
Best price: ₹348
MRP: ₹366
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Matilda ER

Matilda ER contains Methylcobalamin (1500mcg) + Pregabalin (75mg). It belongs to the B-complex vitamin and Gabapentinoid class of medicines.

Uses of Matilda ER

Matilda PG ER Tablet is used in the treatment of neuropathic pain.

Key benefits

  • Corrects a deficiency that causes tiredness and nerve symptoms
  • Supports the formation of healthy red blood cells
  • Generally well tolerated
  • Works on nerve pain that ordinary painkillers do not touch
  • Also used to control fits

How Matilda ER works

Matilda PG ER Tablet is a combination of two medicines: Methylcobalamin/Mecobalamin and Pregabalin. Methylcobalamin/Mecobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

How to take Matilda ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Matilda PG ER Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Matilda ER

Most side effects of Matilda ER are mild and settle as the body adjusts. Reported side effects include:

  • Dizziness Sleepiness Tiredness Uncoordinated body movements

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Matilda ER

PregnancyMatilda PG ER Tablet may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingMatilda PG ER Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
AlcoholMatilda PG ER Tablet may cause excessive drowsiness and calmness with alcohol.
DrivingDo not drive or operate machinery while taking this medicine.
KidneyMatilda PG ER Tablet should be used with caution in patients with kidney disease. Dose adjustment of Matilda PG ER Tablet may be needed. Please consult your doctor.
LiverMatilda PG ER Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Matilda PG ER Tablet may not be needed in these patients. Please consult your doctor.
Habit formingYes

Warnings and precautions

Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.

Do not take Matilda ER if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.

How to store Matilda ER

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Matilda ER

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Matilda PG ER Tablet for treating and preventing nerve pain.</li> <li>Its side effects are usually mild and temporary.</li> <li>It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.</li> <li>To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.</li> <li>Avoid consuming alcohol when taking Matilda PG ER Tablet, as it may cause excessive sleepiness.</li> <li>Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.</li> <li>Do not stop taking the medication suddenly without talking to your doctor.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
Vitamin supplement and Neuropathic pain agent
Drug class:
B-complex vitamin and Gabapentinoid

Substitutes for Matilda ER

Medicines with the same active ingredient (Methylcobalamin (1500mcg) + Pregabalin (75mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Matilda ER
Diamyelin 50 CapsuleVENREDD PHARMAcapsule · 10`S₹9373% cheaper
Axon Pg TabletNOUVELLE PHARMACEUTICALStablet · 10`S₹11667% cheaper
Pregamerge M SR 75 mg TabletD EARTH PHARMACEUTICALStablet · 10`S₹13362% cheaper
Medineuron Pg SRMMC HEALTHCARE LTD10`S₹14359% cheaper
Preganerve M SREAST WEST PHARMA10`S₹14359% cheaper
Meconerv P SR TabletMICRO LABStablet · 10S₹14858% cheaper
Pregabrit TabletElbrit LIfe Sciencestablet · 10`S₹16652% cheaper
Renerve P CapsuleERIS LIFE SCIENCES PVT LTDcapsule · 10`S₹19045% cheaper
Pregadoc-M 75LUPIN LAB10`S₹20142% cheaper
Pregadoc M SR 75 mg TabletLUPIN LABtablet · 10`S₹20342% cheaper
Axogurd SRALEMBIC PHARMA10`S₹21638% cheaper
Rejunuron Dn TabletFourrts India Laboratories Pvt Ltdtablet · 10`S₹22336% cheaper
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Matilda ER FAQs

What is Matilda ER used for?
Matilda ER is commonly used for Matilda PG ER Tablet is used in the treatment of neuropathic pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Matilda ER?
Matilda ER contains Methylcobalamin (1500mcg) + Pregabalin (75mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Matilda ER?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Matilda ER work?
Matilda PG ER Tablet is a combination of two medicines: Methylcobalamin/Mecobalamin and Pregabalin.
Is Matilda ER a prescription medicine?
Yes. Matilda ER is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Matilda ER?
The side effects reported most often with Matilda ER are Dizziness Sleepiness Tiredness Uncoordinated body movements. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Matilda ER be taken during pregnancy?
Matilda PG ER Tablet may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Matilda ER.
Can I drink alcohol while taking Matilda ER?
Matilda PG ER Tablet may cause excessive drowsiness and calmness with alcohol.
What if I miss a dose of Matilda ER?
Take it as soon as you remember.
Is Matilda ER habit forming?
Yes Take Matilda ER only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Matilda ER?
Diamyelin 50 Capsule has the same active ingredient and strength and is listed from ₹93 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Matilda ER cost on PingMeDoc Pharmacy?
Matilda ER starts at ₹348 (MRP ₹366) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Matilda ER?
Matilda ER is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Matilda ER delivered?
Matilda ER is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Matilda ER, Quick facts

Salt
Methylcobalamin (1500mcg) + Pregabalin (75mg)
Best price
₹348
MRP
₹366
Prescription
Required (Rx)
Schedule
Schedule H
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
Vitamin supplement and Neuropathic pain agent
Drug class
B-complex vitamin and Gabapentinoid
Habit forming
Yes
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Matilda ER.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.