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Prescription requiredPristine Pearl PharmaVitamin supplement and Neuropathic pain agent

Pregaprl M Tablet

Methylcobalamin (1500mcg) + Pregabalin (75mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹257

Pregaprl M Tablet is used for pregaprl M Tablet is used in the treatment of neuropathic pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Methylcobalamin (1500mcg) + Pregabalin (75mg)
Available variants: tablet 1500mcg + 75mg 15`S
Best price: ₹257 (₹17.10 per tablet)
MRP: ₹270
Prescription: Required
Manufacturer: PRISTINE PEARL PHARMA

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Pregaprl M Tablet.

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Pregaprl M Tablet

tablet - 1500mcg + 75mg - 15 S

₹257

₹17.10 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Pregaprl M Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Pregaprl M Tablet

Pregaprl M Tablet contains Methylcobalamin (1500mcg) + Pregabalin (75mg). It belongs to the B-complex vitamin and Gabapentinoid class of medicines.

Uses of Pregaprl M Tablet

Pregaprl M Tablet is used in the treatment of neuropathic pain.

Key benefits

  • Corrects a deficiency that causes tiredness and nerve symptoms
  • Supports the formation of healthy red blood cells
  • Generally well tolerated
  • Works on nerve pain that ordinary painkillers do not touch
  • Also used to control fits

How Pregaprl M Tablet works

Pregaprl M Tablet is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

How to take Pregaprl M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregaprl M Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Pregaprl M Tablet

Most side effects of Pregaprl M are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Stomach upset
  • Harmless bright yellow urine
  • Loose motions
  • Drowsiness
  • Dizziness
  • Swelling of the ankles and feet
  • Weight gain
  • Blurred vision
  • Unsteadiness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pregaprl M Tablet

PregnancyPregaprl M Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingPregaprl M Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
AlcoholPregaprl M Tablet may cause excessive drowsiness and calmness with alcohol.
DrivingDo not drive or operate machinery while taking this medicine.
KidneyPregaprl M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pregaprl M Tablet may be needed. Please consult your doctor.
LiverPregaprl M Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregaprl M Tablet may not be needed in these patients. Please consult your doctor.
Habit formingYes

Warnings and precautions

Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.

Do not take Pregaprl M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.

How to store Pregaprl M Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Pregaprl M Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Pregaprl M Tablet for treating and preventing nerve pain.</li> <li>Its side effects are usually mild and temporary.</li> <li>It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.</li> <li>To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.</li> <li>Avoid consuming alcohol when taking Pregaprl M Tablet , as it may cause excessive sleepiness.</li> <li>Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.</li> <li>Do not stop taking the medication suddenly without talking to your doctor.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
PRISTINE PEARL PHARMA
Therapeutic class:
Vitamin supplement and Neuropathic pain agent
Drug class:
B-complex vitamin and Gabapentinoid

Substitutes for Pregaprl M Tablet

Medicines with the same active ingredient (Methylcobalamin (1500mcg) + Pregabalin (75mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Pregaprl M Tablet
Diamyelin 50 CapsuleVENREDD PHARMAcapsule · 10`S₹9364% cheaper
Axon Pg TabletNOUVELLE PHARMACEUTICALStablet · 10`S₹11655% cheaper
Pregamerge M SR 75 mg TabletD EARTH PHARMACEUTICALStablet · 10`S₹13348% cheaper
Medineuron Pg SRMMC HEALTHCARE LTD10`S₹14344% cheaper
Preganerve M SREAST WEST PHARMA10`S₹14344% cheaper
Meconerv P SR TabletMICRO LABStablet · 10S₹14842% cheaper
Pregabrit TabletElbrit LIfe Sciencestablet · 10`S₹16635% cheaper
Renerve P CapsuleERIS LIFE SCIENCES PVT LTDcapsule · 10`S₹19026% cheaper
Pregadoc-M 75LUPIN LAB10`S₹20122% cheaper
Pregadoc M SR 75 mg TabletLUPIN LABtablet · 10`S₹20321% cheaper
Axogurd SRALEMBIC PHARMA10`S₹21616% cheaper
Rejunuron Dn TabletFourrts India Laboratories Pvt Ltdtablet · 10`S₹22313% cheaper
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Pregaprl M Tablet FAQs

What is Pregaprl M Tablet used for?
Pregaprl M Tablet is commonly used for Pregaprl M Tablet is used in the treatment of neuropathic pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Pregaprl M Tablet?
Pregaprl M Tablet contains Methylcobalamin (1500mcg) + Pregabalin (75mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Pregaprl M Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Pregaprl M Tablet work?
Pregaprl M Tablet is a combination of two medicines: Methylcobalamin and Pregabalin.
Is Pregaprl M Tablet a prescription medicine?
Yes. Pregaprl M Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Pregaprl M Tablet?
The side effects reported most often with Pregaprl M are Nausea, Stomach upset, Harmless bright yellow urine, Loose motions, Drowsiness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Pregaprl M Tablet be taken during pregnancy?
Pregaprl M Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Pregaprl M.
Can I drink alcohol while taking Pregaprl M Tablet?
Pregaprl M Tablet may cause excessive drowsiness and calmness with alcohol.
What if I miss a dose of Pregaprl M Tablet?
Take it as soon as you remember.
Is Pregaprl M Tablet habit forming?
Yes Take Pregaprl M only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Pregaprl M Tablet?
Diamyelin 50 Capsule has the same active ingredient and strength and is listed from ₹93 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Pregaprl M Tablet cost on PingMeDoc Pharmacy?
Pregaprl M Tablet starts at ₹257 (MRP ₹270) on PingMeDoc Pharmacy. Available in tablet 1500mcg + 75mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Pregaprl M Tablet?
Pregaprl M Tablet is manufactured by PRISTINE PEARL PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Pregaprl M Tablet delivered?
Pregaprl M Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Pregaprl M Tablet, Quick facts

Salt
Methylcobalamin (1500mcg) + Pregabalin (75mg)
Form
tablet
Best price
₹257 (₹17.10 per tablet)
MRP
₹270
Prescription
Required (Rx)
Schedule
Schedule H
Brand
PRISTINE PEARL PHARMA
Manufacturer
PRISTINE PEARL PHARMA
Therapeutic class
Vitamin supplement and Neuropathic pain agent
Drug class
B-complex vitamin and Gabapentinoid
Habit forming
Yes
Variants
tablet 1500mcg + 75mg 15`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Pregaprl M Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.