
Ambroprl Respules
Pristine Pearl Pharma - Respule - 5 X2 ml
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Prescription required
Methylcobalamin (1500mcg) + Pregabalin (75mg)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹257
Pregaprl M Tablet is used for pregaprl M Tablet is used in the treatment of neuropathic pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Medicines with the same active ingredient and strength as Pregaprl M Tablet.
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Pregaprl M Tablet
tablet - 1500mcg + 75mg - 15 S
₹257
₹17.10 per tablet
NOUVELLE PHARMACEUTICALS · tablet - 1500mcg + 75mg - 10 S · Rx
₹116
₹11.58 per tablet
D EARTH PHARMACEUTICALS · tablet - 75 mg - 10 S · Rx
₹133
₹13.30 per tablet
MICRO LABS · tablet - 1500mcg + 75mg - 10 S · Rx
₹148
₹14.78 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Pregaprl M Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Pregaprl M Tablet contains Methylcobalamin (1500mcg) + Pregabalin (75mg). It belongs to the B-complex vitamin and Gabapentinoid class of medicines.
Pregaprl M Tablet is used in the treatment of neuropathic pain.
Pregaprl M Tablet is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregaprl M Tablet may be taken with or without food, but it is better to take it at a fixed time.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Pregaprl M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregaprl M Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Pregaprl M Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Pregaprl M Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Pregaprl M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pregaprl M Tablet may be needed. Please consult your doctor. |
| Liver | Pregaprl M Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregaprl M Tablet may not be needed in these patients. Please consult your doctor. |
| Habit forming | Yes |
Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Pregaprl M Tablet for treating and preventing nerve pain.</li> <li>Its side effects are usually mild and temporary.</li> <li>It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.</li> <li>To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.</li> <li>Avoid consuming alcohol when taking Pregaprl M Tablet , as it may cause excessive sleepiness.</li> <li>Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.</li> <li>Do not stop taking the medication suddenly without talking to your doctor.</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Methylcobalamin (1500mcg) + Pregabalin (75mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Pregaprl M Tablet |
|---|---|---|---|
| Diamyelin 50 CapsuleVENREDD PHARMA | capsule · 10`S | ₹93 | 64% cheaper |
| Axon Pg TabletNOUVELLE PHARMACEUTICALS | tablet · 10`S | ₹116 | 55% cheaper |
| Pregamerge M SR 75 mg TabletD EARTH PHARMACEUTICALS | tablet · 10`S | ₹133 | 48% cheaper |
| Medineuron Pg SRMMC HEALTHCARE LTD | 10`S | ₹143 | 44% cheaper |
| Preganerve M SREAST WEST PHARMA | 10`S | ₹143 | 44% cheaper |
| Meconerv P SR TabletMICRO LABS | tablet · 10S | ₹148 | 42% cheaper |
| Pregabrit TabletElbrit LIfe Sciences | tablet · 10`S | ₹166 | 35% cheaper |
| Renerve P CapsuleERIS LIFE SCIENCES PVT LTD | capsule · 10`S | ₹190 | 26% cheaper |
| Pregadoc-M 75LUPIN LAB | 10`S | ₹201 | 22% cheaper |
| Pregadoc M SR 75 mg TabletLUPIN LAB | tablet · 10`S | ₹203 | 21% cheaper |
| Axogurd SRALEMBIC PHARMA | 10`S | ₹216 | 16% cheaper |
| Rejunuron Dn TabletFourrts India Laboratories Pvt Ltd | tablet · 10`S | ₹223 | 13% cheaper |

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.