
Adaple-C Gel
Wallace Pharmaceuticals Pvt Ltd - Gel - 15 G
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Folic Acid (1mg) + Methotrexate (7.5mg)
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We'll let you know the moment Mext 7.5-F Tablet Kit is back in stock.
Mext 7.5-F Tablet Kit is used for mext 7.5 F Combipack is used in the treatment of rheumatoid arthritis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Mext 7.5-F Tablet Kit contains Folic Acid (1mg) + Methotrexate (7.5mg). It belongs to the B-complex vitamin and Enzyme / disease-modifying anti-rheumatic agent class of medicines.
Mext 7.5 F Combipack is used in the treatment of rheumatoid arthritis.
Mext 7.5 F Combipack is a combination of two medicines: Methotrexate and Folic Acid. Methotrexate is an anticancer and immunosuppressive medication. It works in cancer by slowing the growth of cancer cells by blocking building blocks that cancer cells need to grow. It also works in autoimmune disease by decreasing the activity of body's immune system and prevents the body from attacking itself. Folic Acid, a form of vitamin B is added to prevent Folic Acid deficiency caused by Methotrexate.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mext 7.5 F Combipack may be taken with or without food, but it is better to take it at a fixed time.<br>Take it with food to avoid stomach upset.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Contact your doctor for advice. Do not take the missed weekly dose together with the next one.
An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Mext 7.5-F are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Mext 7.5 F Combipack is highly unsafe to use during pregnancy.<br>Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor. |
|---|---|
| Breastfeeding | Mext 7.5 F Combipack is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable. |
| Alcohol | Taking Methotrxate with alcohol increases the risk of liver damage. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Mext 7.5 F Combipack is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mext 7.5 F Combipack may not be needed in these patients. Please consult your doctor. |
| Liver | Mext 7.5 F Combipack is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mext 7.5 F Combipack may not be needed in these patients. Please consult your doctor. |
| Habit forming | No |
Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack. For arthritis and psoriasis this medicine is taken ONCE A WEEK, on the same day each week. Taking it daily by mistake causes severe, sometimes fatal harm — check the day on your pack and confirm it with your pharmacist. Take folic acid on the days your doctor has specified, but not on the same day as the methotrexate unless told to. Report mouth ulcers, sore throat, fever, unusual bruising or breathlessness immediately.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.
Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for. Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.