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Prescription requiredRpg Life Sciences LimitedAnalgesic and anti-inflammatory and Anti-emetic

Naprosyn D 250 Tablet

Naproxen (250 mg) + Domperidone (10 mg)

Naprosyn D 250 Tablet is used for relieves pain, reduces inflammation, decreases fever.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹86₹8.56 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Naproxen (250 mg) + Domperidone (10 mg)
Available variants: tablet 10 Tablet
Best price: ₹86 (₹8.56 per tablet)
Prescription: Required
Manufacturer: RPG LIFE SCIENCES LIMITED

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Naprosyn D 250 Tablet.

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Naprosyn D 250 Tablet

tablet - 10 Tablet

₹86

₹8.56 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Naprosyn D 250 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Naprosyn D 250 Tablet

Naprosyn D 250 Tablet contains Naproxen (250 mg) + Domperidone (10 mg). It belongs to the Non-steroidal anti-inflammatory drug and Anti-emetic / prokinetic class of medicines.

Uses of Naprosyn D 250 Tablet

  • relieves pain
  • reduces inflammation
  • decreases fever

Key benefits

  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury
  • Rapid relief of nausea and vomiting
  • Helps bloating and early fullness

How Naprosyn D 250 Tablet works

Peripheral dopamine antagonist that increases gastric motility.

How to take Naprosyn D 250 Tablet

Take with food, do not crush or chew, do not exceed recommended dose

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Naprosyn D 250 Tablet

Most side effects of Naprosyn D are mild and settle as the body adjusts. Reported side effects include:

  • Dry mouth
  • headache; rare cardiac effects.

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Naprosyn D 250 Tablet

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Avoid in patients with significant cardiac disease; use lowest effective duration.

Do not take Naprosyn D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives.

How to store Naprosyn D 250 Tablet

Store below 25°C.

Expert advice for Naprosyn D 250 Tablet

Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache. Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.

Manufacturer and class

Manufacturer:
RPG LIFE SCIENCES LIMITED
Therapeutic class:
Analgesic and anti-inflammatory and Anti-emetic
Drug class:
Non-steroidal anti-inflammatory drug and Anti-emetic / prokinetic

Substitutes for Naprosyn D 250 Tablet

Medicines with the same active ingredient (Naproxen (250 mg) + Domperidone (10 mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Naprosyn D 250 Tablet
Quickrel 10/250 TabletDr Reddys Laboratories Ltdtablet · 10`S₹7710% cheaper
Napcox D 250 mg TabletMEXICAN WAVE PHARMAtablet · 10`S₹834% cheaper
Domoxen-250 TabletLARENONtablet · 10`S₹851% cheaper
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Naprosyn D 250 Tablet FAQs

What is Naprosyn D 250 Tablet used for?
Naprosyn D 250 Tablet is commonly used for relieves pain, reduces inflammation, decreases fever. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Naprosyn D 250 Tablet?
Naprosyn D 250 Tablet contains Naproxen (250 mg) + Domperidone (10 mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Naprosyn D 250 Tablet?
Take with food, do not crush or chew, do not exceed recommended dose Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Naprosyn D 250 Tablet work?
Peripheral dopamine antagonist that increases gastric motility.
Is Naprosyn D 250 Tablet a prescription medicine?
Yes. Naprosyn D 250 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Naprosyn D 250 Tablet?
The side effects reported most often with Naprosyn D are Dry mouth, headache; rare cardiac effects.. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Naprosyn D 250 Tablet be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Naprosyn D.
Can I drink alcohol while taking Naprosyn D 250 Tablet?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Naprosyn D 250 Tablet?
Take it as soon as you remember.
Is Naprosyn D 250 Tablet habit forming?
No. Naprosyn D 250 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Naprosyn D 250 Tablet?
Quickrel 10/250 Tablet has the same active ingredient and strength and is listed from ₹77 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Naprosyn D 250 Tablet cost on PingMeDoc Pharmacy?
Naprosyn D 250 Tablet starts at ₹86 on PingMeDoc Pharmacy. Available in tablet 10 Tablet. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Naprosyn D 250 Tablet?
Naprosyn D 250 Tablet is manufactured by RPG LIFE SCIENCES LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Naprosyn D 250 Tablet delivered?
Naprosyn D 250 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Naprosyn D 250 Tablet, Quick facts

Salt
Naproxen (250 mg) + Domperidone (10 mg)
Form
tablet
Best price
₹86 (₹8.56 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
RPG LIFE SCIENCES LIMITED
Manufacturer
RPG LIFE SCIENCES LIMITED
Therapeutic class
Analgesic and anti-inflammatory and Anti-emetic
Drug class
Non-steroidal anti-inflammatory drug and Anti-emetic / prokinetic
Habit forming
No
Variants
tablet 10 Tablet
Delivery
Standard across India

References

The information on Naprosyn D 250 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Naprosyn D 250 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.