
Adrole 0.5
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Metformin (500mg) + Benfotiamine (75mg)
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New Metben is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
New Metben contains Metformin (500mg) + Benfotiamine (75mg). It belongs to the Biguanide and B-complex vitamin class of medicines.
Treatment of Type 2 diabetes mellitus
Metben Tablet is a combination of two medicines:.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metben Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of New Metben are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Information regarding the use of Metben Tablet during pregnancy is not available. Please consult your doctor. |
|---|---|
| Breastfeeding | Metben Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Alcohol | It is unsafe to consume alcohol with Metben Tablet. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Metben Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metben Tablet may be needed. Please consult your doctor.Use of Metben Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. |
| Liver | Metben Tablet should be used with caution in patients with liver disease. Dose adjustment of Metben Tablet may be needed. Please consult your doctor.Metben Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease. |
| Habit forming | No |
Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.