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Oncotrex-5 mg
Methotrexate (5mg)
₹96MRP ₹1015% offIn stock
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Oncotrex-5 mg is used for treatment of Cancer Treatment of Rheumatoid arthritis Treatment of Psoriasis Treatment of Crohn’s disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Methotrexate (5mg)
Available variants: 5 mg 10`S
Best price: ₹96
MRP: ₹101
Prescription: Required
Manufacturer: SUN PHARMA 2
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Oncotrex-5 mg
Oncotrex-5 mg contains Methotrexate (5mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent class of medicines.
Uses of Oncotrex-5 mg
Treatment of Cancer Treatment of Rheumatoid arthritis Treatment of Psoriasis Treatment of Crohn’s disease
Key benefits
- In Treatment of Cancer Oncotrex 5 Tablet works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers
- such as acute leukemias
- non-Hodgkin’s lymphoma
- and solid tumors found in the breast
- lung
- bladder
- head
- and neck
- as well as cervical
- ovarian
- and testicular cancer. It may be given alone or in combination with other medicines. In Treatment of Rheumatoid arthritis Oncotrex 5 Tablet is typically used to treat severe rheumatoid arthritis when other treatments have not been effective. As a second-line treatment
- it works by suppressing the immune system
- which helps reduce inflammation
- pain
- stiffness
- and improves joint function. Follow your doctor’s instructions carefully
- taking it exactly as prescribed
- and for the full duration. It may take several months to show full effects. Do not take more than the prescribed dose. In Treatment of Psoriasis Oncotrex 5 Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Oncotrex 5 Tablet works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Treatment of Crohn’s disease Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in the abdomen. Oncotrex 5 Tablet helps reduce the inflammation
- relieve the symptoms
- and prevent them from coming back. Show More
How Oncotrex-5 mg works
Oncotrex 5 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division, and leads to anti-inflammatory actions. Oncotrex 5 Tablet kills cancer cells by preventing them from making DNA. Oncotrex 5 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Oncotrex 5 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to the intestine in Crohn's disease.
How to take Oncotrex-5 mg
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oncotrex 5 Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Oncotrex 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Oncotrex-5 mg
Most side effects of Oncotrex-5 mg are mild and settle as the body adjusts. Reported side effects include:
- Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Oncotrex-5 mg
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Warnings and precautions
Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack. For arthritis and psoriasis this medicine is taken ONCE A WEEK, on the same day each week. Taking it daily by mistake causes severe, sometimes fatal harm — check the day on your pack and confirm it with your pharmacist. Take folic acid on the days your doctor has specified, but not on the same day as the methotrexate unless told to. Report mouth ulcers, sore throat, fever, unusual bruising or breathlessness immediately.
Do not take Oncotrex-5 mg if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.
Interactions with other medicines
Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.
How to store Oncotrex-5 mg
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Oncotrex-5 mg
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. Oncotrex 5 Tablet may take from weeks to months for Oncotrex 5 Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood tests done to monitor your kidney function, liver function, and the level of blood cells in your blood. Avoid drinking alcohol while taking this medicine, as it may increase the risk of side effects.
Manufacturer and class
- Manufacturer:
- SUN PHARMA 2
- Therapeutic class:
- ANTI NEOPLASTICS
- Drug class:
- Enzyme / disease-modifying anti-rheumatic agent
- Chemical class:
- Glutamic acid derivative
Substitutes for Oncotrex-5 mg
Medicines with the same active ingredient (Methotrexate (5mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Oncotrex-5 mg |
|---|---|---|---|
| Mexate 5 mg TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹96 | same price |
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Oncotrex-5 mg FAQs
What is Oncotrex-5 mg used for?
Oncotrex-5 mg is commonly used for Treatment of Cancer Treatment of Rheumatoid arthritis Treatment of Psoriasis Treatment of Crohn’s disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Oncotrex-5 mg?
Oncotrex-5 mg contains Methotrexate (5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Oncotrex-5 mg?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Oncotrex-5 mg work?
Oncotrex 5 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division, and leads to anti-inflammatory actions.
Is Oncotrex-5 mg a prescription medicine?
Yes. Oncotrex-5 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Oncotrex-5 mg?
The side effects reported most often with Oncotrex-5 mg are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Oncotrex-5 mg be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Oncotrex-5 mg.
Can I drink alcohol while taking Oncotrex-5 mg?
Alcohol UNSAFE
What if I miss a dose of Oncotrex-5 mg?
If you miss a dose of Oncotrex 5 Tablet, take it as soon as possible.
Is Oncotrex-5 mg habit forming?
No. Oncotrex-5 mg is not known to be habit forming when taken as prescribed.
How much does Oncotrex-5 mg cost on PingMeDoc Pharmacy?
Oncotrex-5 mg starts at ₹96 (MRP ₹101) on PingMeDoc Pharmacy. Available in 5 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Oncotrex-5 mg?
Oncotrex-5 mg is manufactured by SUN PHARMA 2. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Oncotrex-5 mg delivered?
Oncotrex-5 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Oncotrex-5 mg, Quick facts
- Salt
- Methotrexate (5mg)
- Best price
- ₹96
- MRP
- ₹101
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- SUN PHARMA 2
- Manufacturer
- SUN PHARMA 2
- Therapeutic class
- ANTI NEOPLASTICS
- Drug class
- Enzyme / disease-modifying anti-rheumatic agent
- Chemical class
- Glutamic acid derivative
- Action class
- Antimetabolite- Methotrexate
- Habit forming
- No
- Variants
- 5 mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Oncotrex-5 mg.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.