Polypin Capsule

Composition of Polypin Capsule

Polypin Capsule contains Atorvastatin (10mg) + Ramipril (2.5mg) + Aspirin (75mg) + Metoprolol (25mg). It belongs to the Statin / lipid modifier, Angiotensin receptor blocker / ACE inhibitor, Blood thinner and Beta blocker class of medicines.

Uses of Polypin Capsule

• This medicine is used in the treatment of high cholesterol
• prevention of heart attack and stroke
• high blood pressure
• heart failure
• diabetic kidney disease
• prevention of heart attack
• prevention of stroke
• blood clots
• angina and irregular heartbeat.

Key benefits

• Proven to reduce heart attacks and strokes
• Usually taken once a day
• Benefit continues for as long as you take it
• Protects the kidneys in diabetes
• Reduces the long-term risk of stroke and heart attack
• Substantially reduces the risk of heart attack and stroke
• Reduces the risk of a further heart attack
• Controls rapid and irregular heart rhythms
• Improves survival in heart failure

How Polypin Capsule works

This medicine combines 4 active ingredients: Atorvastatin, Ramipril, Aspirin and Metoprolol. Atorvastatin lowers the amount of bad cholesterol your liver makes and helps clear it from the blood, which slows the furring of your arteries. Ramipril relaxes and widens your blood vessels by blocking a hormone that narrows them, so your heart does not have to push as hard and your blood pressure falls. Aspirin makes your blood less likely to form a clot, which protects the narrowed arteries of the heart and brain. Metoprolol slows the heart and reduces the force of each beat by blocking the effect of adrenaline, so the heart works less hard and uses less oxygen.

How to take Polypin Capsule

Swallow the capsule whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or without food, usually in the evening. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely to cause immediate harm but may increase the risk of muscle and liver injury. It can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. It can cause serious and difficult-to-control bleeding. It can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Polypin Capsule

Most side effects of Polypin are mild and settle as the body adjusts. Reported side effects include:

• Muscle aches
• Headache
• Nausea
• Constipation or loose motions
• Raised liver enzymes
• Dizziness on standing up
• Tiredness
• Raised potassium
• Dry cough
• Bruising easily
• Bleeding for longer from cuts
• Nosebleeds
• Indigestion
• Stomach pain
• Cold hands and feet
• Slow pulse
• Dizziness
• Disturbed sleep
• Breathlessness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Polypin Capsule

Warnings and precautions

Report unexplained muscle pain, tenderness or weakness — especially with fever or dark urine — without waiting for your next appointment. Your doctor will check your liver with a blood test before starting and from time to time afterwards. Cholesterol medicines work silently; you will not feel their benefit, and that is not a reason to stop. Tell your doctor if you develop new or worsening diabetes symptoms. Stand up slowly for the first few days — dizziness on rising is common when you start or your dose goes up. Stop and seek urgent care if your lips, tongue, face or throat swell, or you have difficulty breathing. A persistent dry, tickly cough can be caused by the ACE inhibitor group; tell your doctor rather than stopping on your own, as an alternative exists. Your doctor will check your kidney function and potassium after starting and after any dose change. Do not use salt substitutes containing potassium without asking your doctor. Seek urgent care for black or tarry stools, blood in the vomit or urine, a severe headache, or bleeding that will not stop. Tell every doctor and dentist treating you that you are on a blood thinner, well before any procedure. Never stop this medicine on your own before surgery or dental work — stopping it carries its own risk, and the decision is your doctor's. Avoid contact sports and take care with razors and sharp tools. Aspirin must not be given to children or teenagers with a fever or a viral illness — it is linked to Reye's syndrome, a rare but serious condition affecting the brain and liver. Low-dose aspirin for the heart is a lifelong treatment. Do not stop it before surgery or dental work without asking the doctor who prescribed it. Never stop this medicine suddenly. Stopping abruptly can cause a sharp rise in blood pressure, worsening chest pain or a heart attack — your doctor will reduce it gradually. Tell your doctor if you have asthma or long-standing lung disease; this group can tighten the airways. If you have diabetes, be aware that this medicine can mask the early warning signs of low blood sugar, apart from sweating. Report a resting pulse that is persistently very slow, or fainting.

Do not take Polypin if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be used in pregnancy or while breastfeeding. Not for people with active liver disease. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines. Not for people with active bleeding, a bleeding disorder, or a recent bleed into the brain. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma.

Interactions with other medicines

Grapefruit juice raises the level of some statins — avoid it. Certain antibiotics, antifungals and fibrates increase the risk of muscle damage when combined. Anti-inflammatory painkillers reduce the effect and can harm the kidneys when combined. Potassium supplements, potassium-sparing water tablets and salt substitutes can push potassium too high. Lithium levels rise when taken with these medicines. Anti-inflammatory painkillers, including over-the-counter ones, sharply raise the bleeding risk. Combining two blood thinners multiplies the risk — never add one yourself. Tell your doctor about all herbal products; several affect clotting. Combining with verapamil or diltiazem can slow the heart dangerously. Tell your doctor about diabetes medicines and about any asthma inhaler.

How to store Polypin Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Polypin Capsule

Continue your diet, exercise and, above all, stopping smoking — the medicine adds to these, not replaces them. Get your lipid profile repeated as your doctor advises. Blood pressure medicines work only while you take them — do not stop because you feel well. Tell your doctor at once if you become pregnant or are planning a pregnancy. Keep a home blood-pressure record if your doctor has asked for one. Carry a card or note saying which blood thinner you take. Take it at the same time every day; a missed dose leaves you less protected. Use paracetamol rather than an anti-inflammatory for ordinary aches, unless your doctor says otherwise. Take it at the same time each day and do not miss doses. Learn to check your own pulse, and report a persistently slow one.

Manufacturer and class

Manufacturer:

XEMEX PHARMA

Therapeutic class:

Lipid-lowering agent, Anti-hypertensive and Antiplatelet / anticoagulant

Drug class:

Statin / lipid modifier, Angiotensin receptor blocker / ACE inhibitor, Blood thinner and Beta blocker