Pregalin M SR 150

Composition of Pregalin M SR 150

Pregalin M SR 150 contains Pregabalin 150 mg (sustained release). It belongs to the Gabapentinoid (GABA analogue; alpha-2-delta calcium channel ligand) class of medicines.

Uses of Pregalin M SR 150

• Neuropathic (nerve) pain due to diabetes
• shingles (post-herpetic neuralgia) or spinal cord injury; fibromyalgia; adjunct treatment of partial-onset seizures (as add-on therapy)

Key benefits

• Relieves neuropathic (nerve) pain
• Reduces burning/tingling sensations
• Improves sleep disturbance associated with nerve pain
• Helps in fibromyalgia pain control
• Add-on control of partial seizures

How Pregalin M SR 150 works

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS. This reduces release of excitatory neurotransmitters and decreases abnormal nerve signaling, relieving neuropathic pain and helping control seizures.

How to take Pregalin M SR 150

Oral sustained-release tablet. Swallow whole with water; do not crush, break or chew. Take once daily as prescribed, preferably at the same time each day; may be taken with or without food. Do not stop suddenly—taper as advised by the doctor.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Pregalin M SR as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Pregalin M SR than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Pregalin M SR 150

Most side effects of Pregalin M SR are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• sleepiness (somnolence)
• blurred vision
• dry mouth
• weight gain
• peripheral edema (swelling)
• fatigue
• headache
• constipation
• difficulty concentrating

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pregalin M SR 150

Warnings and precautions

May cause dizziness/drowsiness—avoid driving or operating machinery until effects are known. Use with caution in kidney disease (dose adjustment required). Can cause swelling/weight gain; caution in heart failure. Rare risk of allergic reactions/angioedema and vision changes—seek medical help if swelling of face/lips, rash, or breathing difficulty occurs. May increase suicidal thoughts in some patients—monitor mood/behavior changes. Do not discontinue abruptly to avoid withdrawal symptoms.

Interactions with other medicines

Alcohol and other CNS depressants (opioids, benzodiazepines, sedating antihistamines) may increase drowsiness/respiratory depression risk; Opioids (e.g., oxycodone, tramadol) increase sedation and constipation risk; ACE inhibitors may increase risk of angioedema; Antidiabetic thiazolidinediones (pioglitazone, rosiglitazone) may increase edema/weight gain

How to store Pregalin M SR 150

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Manufacturer and class

Manufacturer:

TORRENT PHARMACEUTICALS

Therapeutic class:

Anti-neuropathic pain agent / Anticonvulsant

Drug class:

Gabapentinoid (GABA analogue; alpha-2-delta calcium channel ligand)