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Prescription requiredNeuropathic pain agent and Vitamin supplement

Prigma M Capsule

Pregabalin (75mg) + Methylcobalamin (750mcg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹162

Prigma M Capsule is used for this medicine is used in the treatment of nerve pain, diabetic neuropathy, pain after shingles, fibromyalgia, epilepsy, vitamin b deficiency, nerve pain and tingling, anaemia and tiredness due to deficiency.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Pregabalin (75mg) + Methylcobalamin (750mcg)
Available variants: 1X10
Best price: ₹162
MRP: ₹170
Prescription: Required

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Prigma M Capsule

Prigma M Capsule contains Pregabalin (75mg) + Methylcobalamin (750mcg). It belongs to the Gabapentinoid and B-complex vitamin class of medicines.

Uses of Prigma M Capsule

  • This medicine is used in the treatment of nerve pain
  • diabetic neuropathy
  • pain after shingles
  • fibromyalgia
  • epilepsy
  • vitamin b deficiency
  • nerve pain and tingling
  • anaemia and tiredness due to deficiency.

Key benefits

  • Works on nerve pain that ordinary painkillers do not touch
  • Also used to control fits
  • Corrects a deficiency that causes tiredness and nerve symptoms
  • Supports the formation of healthy red blood cells
  • Generally well tolerated

How Prigma M Capsule works

This medicine combines 2 active ingredients: Pregabalin and Methylcobalamin. Pregabalin calms the over-active nerve signals that cause burning, shooting and tingling pain. Methylcobalamin replaces a B vitamin your body needs to make red blood cells, to keep nerves healthy and to release energy from food.

How to take Prigma M Capsule

Swallow the capsule whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or without food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Prigma M Capsule

Most side effects of Prigma M are mild and settle as the body adjusts. Reported side effects include:

  • Drowsiness
  • Dizziness
  • Swelling of the ankles and feet
  • Weight gain
  • Blurred vision
  • Unsteadiness
  • Nausea
  • Stomach upset
  • Harmless bright yellow urine
  • Loose motions

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Prigma M Capsule

PregnancyNot recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingDo not drive or operate machinery while taking this medicine.
KidneyConsult your doctor if you have kidney disease.
LiverUse with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.
Habit formingYes

Warnings and precautions

This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.

Do not take Prigma M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.

How to store Prigma M Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Prigma M Capsule

Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

Manufacturer and class

Therapeutic class:
Neuropathic pain agent and Vitamin supplement
Drug class:
Gabapentinoid and B-complex vitamin

Substitutes for Prigma M Capsule

Medicines with the same active ingredient (Pregabalin (75mg) + Methylcobalamin (750mcg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Prigma M Capsule
Pregafic 25 M TabletFICUS LIFE SCIENCEStablet · 10`S₹6063% cheaper
Me-Pr CapsuleSYSTOPIC LABcapsule · 10`S₹9939% cheaper
PrerenerBIOCEUTICS10`S₹10038% cheaper
Rejuvin Gold CapsuleELANCE HEALTH CAREcapsule · 10`S₹10535% cheaper
Startnerve 75 mg CapsuleSANZ PHARMACEUTICALScapsule · 10`S₹10734% cheaper
Gaba CadSHRRISHTI HEALTHCARE PRODUCTS(I) PVT LTD10`S₹10734% cheaper
Fixmyel CapsuleEFFRA LIFE SCIENCEScapsule · 10`S₹13318% cheaper
Transnerv-PgPRIMUS PHARMA10`S₹13616% cheaper
Yogamin M 75 CapsuleHIGLANCEcapsule · 10`S₹14013% cheaper
Myliday P CapsuleCOGNYZON PHARMACEUTICALScapsule · 10`S₹14312% cheaper
Neuroprime-Pg CapsulePRIMUS PHARMAcapsule · 10`S₹1498% cheaper
Neurica TabletMICRO LABStablet · 10`S₹1507% cheaper
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Prigma M Capsule FAQs

What is Prigma M Capsule used for?
Prigma M Capsule is commonly used for This medicine is used in the treatment of nerve pain, diabetic neuropathy, pain after shingles, fibromyalgia, epilepsy, vitamin b deficiency, nerve pain and tingling, anaemia and tiredness due to deficiency. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Prigma M Capsule?
Prigma M Capsule contains Pregabalin (75mg) + Methylcobalamin (750mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Prigma M Capsule?
Swallow the capsule whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Prigma M Capsule work?
This medicine combines 2 active ingredients: Pregabalin and Methylcobalamin.
Is Prigma M Capsule a prescription medicine?
Yes. Prigma M Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Prigma M Capsule?
The side effects reported most often with Prigma M are Drowsiness, Dizziness, Swelling of the ankles and feet, Weight gain, Blurred vision. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Prigma M Capsule be taken during pregnancy?
Not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Prigma M.
Can I drink alcohol while taking Prigma M Capsule?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Prigma M Capsule?
Take it as soon as you remember.
Is Prigma M Capsule habit forming?
Yes Take Prigma M only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Prigma M Capsule?
Pregafic 25 M Tablet has the same active ingredient and strength and is listed from ₹60 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Prigma M Capsule cost on PingMeDoc Pharmacy?
Prigma M Capsule starts at ₹162 (MRP ₹170) on PingMeDoc Pharmacy. Available in 1X10. Final price is confirmed at checkout and may vary by variant and location.
How is Prigma M Capsule delivered?
Prigma M Capsule is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Prigma M Capsule, Quick facts

Salt
Pregabalin (75mg) + Methylcobalamin (750mcg)
Best price
₹162
MRP
₹170
Prescription
Required (Rx)
Therapeutic class
Neuropathic pain agent and Vitamin supplement
Drug class
Gabapentinoid and B-complex vitamin
Habit forming
Yes
Variants
1X10
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Prigma M Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.