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Prescription requiredCipla LimitedRESPIRATORY

Seroflo 250 Synchrobreathe

Salmeterol (25mcg) + Fluticasone Propionate (250mcg)

₹990MRP ₹1,042In stock
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Delivery across India: ₹49 delivery, free above ₹999. Chennai express delivery is chargeable.

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Seroflo 250 Synchrobreathe is used for treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Salmeterol (25mcg) + Fluticasone Propionate (250mcg)
Available variants: tablet 25mcg + 250mcg 120MD
Best price: ₹990
MRP: ₹1,042
Prescription: Required
Manufacturer: CIPLA LIMITED

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Seroflo 250 Synchrobreathe

Seroflo 250 Synchrobreathe contains Salmeterol (25mcg) + Fluticasone Propionate (250mcg). It belongs to the Combination inhaler (Long-acting beta-agonist and corticosteroid) class of medicines.

Uses of Seroflo 250 Synchrobreathe

Treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD)

Key benefits

  • In Treatment of Asthma Seroflo 250 Synchrobreathe can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust
  • pollen
  • pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing
  • coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms. In Treatment of Chronic obstructive pulmonary disease (COPD) Seroflo 250 Synchrobreathe helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest
  • shortness of breath
  • wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor. Show More

How Seroflo 250 Synchrobreathe works

Seroflo 250 Synchrobreathe is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

How to take Seroflo 250 Synchrobreathe

Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Seroflo 250 Synchrobreathe, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Seroflo 250 Synchrobreathe

Most side effects of Seroflo are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Seroflo 250 Synchrobreathe

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CAUTION
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving UNSAFE
KidneyKidney
LiverLiver
Habit formingNo

Warnings and precautions

Not for acute asthma attacks, use with caution in patients with cardiovascular disorders, diabetes, or thyroid disorders.

Do not take Seroflo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

May interact with beta-blockers, diuretics, and other medications affecting heart rhythm.

How to store Seroflo 250 Synchrobreathe

Store at room temperature, away from light and moisture. Keep out of reach of children.

Expert advice for Seroflo 250 Synchrobreathe

This medicine is for inhalation only. The tablet should not be swallowed. It should be taken at the same time each day. It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help. Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat. Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using. Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Seroflo 250 Synchrobreathe can lower blood potassium level. Only miniscule amounts of Seroflo 250 Synchrobreathe may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Manufacturer and class

Manufacturer:
CIPLA LIMITED
Therapeutic class:
RESPIRATORY
Drug class:
Combination inhaler (Long-acting beta-agonist and corticosteroid)

Substitutes for Seroflo 250 Synchrobreathe

Medicines with the same active ingredient (Salmeterol (25mcg) + Fluticasone Propionate (250mcg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Seroflo 250 Synchrobreathe
Airtec Sf 250 DpiGLENMARK PHARMACEUTICALS30`S₹50149% cheaper
Digihaler Sf 250 InhalerGLENMARK PHARMACEUTICALSinhaler · 1`S₹69929% cheaper
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Seroflo 250 Synchrobreathe FAQs

What is Seroflo 250 Synchrobreathe used for?
Seroflo 250 Synchrobreathe is commonly used for Treatment of Asthma Treatment of Chronic obstructive pulmonary disease (COPD). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Seroflo 250 Synchrobreathe?
Seroflo 250 Synchrobreathe contains Salmeterol (25mcg) + Fluticasone Propionate (250mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Seroflo 250 Synchrobreathe?
Check the label for directions before use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Seroflo 250 Synchrobreathe work?
Seroflo 250 Synchrobreathe is a combination of two medicines: Salmeterol and Fluticasone Propionate.
Is Seroflo 250 Synchrobreathe a prescription medicine?
Yes. Seroflo 250 Synchrobreathe is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Seroflo 250 Synchrobreathe?
The side effects reported most often with Seroflo are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Seroflo 250 Synchrobreathe be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Seroflo.
Can I drink alcohol while taking Seroflo 250 Synchrobreathe?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Seroflo 250 Synchrobreathe?
If you miss a dose of Seroflo 250 Synchrobreathe, use it as soon as possible.
Is Seroflo 250 Synchrobreathe habit forming?
No. Seroflo 250 Synchrobreathe is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Seroflo 250 Synchrobreathe?
Airtec Sf 250 Dpi has the same active ingredient and strength and is listed from ₹501 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Seroflo 250 Synchrobreathe cost on PingMeDoc Pharmacy?
Seroflo 250 Synchrobreathe starts at ₹990 (MRP ₹1,042) on PingMeDoc Pharmacy. Available in tablet 25mcg + 250mcg 120MD. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Seroflo 250 Synchrobreathe?
Seroflo 250 Synchrobreathe is manufactured by CIPLA LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Seroflo 250 Synchrobreathe delivered?
Seroflo 250 Synchrobreathe is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Seroflo 250 Synchrobreathe, Quick facts

Salt
Salmeterol (25mcg) + Fluticasone Propionate (250mcg)
Form
tablet
Best price
₹990
MRP
₹1,042
Prescription
Required (Rx)
Schedule
Schedule H
Brand
CIPLA LIMITED
Manufacturer
CIPLA LIMITED
Therapeutic class
RESPIRATORY
Drug class
Combination inhaler (Long-acting beta-agonist and corticosteroid)
Habit forming
No
Variants
tablet 25mcg + 250mcg 120MD
Delivery
Standard across India

References

The information on Seroflo 250 Synchrobreathe is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Indian Pharmacopoeia
  2. CDSCO, manufacturer labeling
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Seroflo 250 Synchrobreathe.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.