Siglifoz 10 mg Tablet

Composition of Siglifoz 10 mg Tablet

Siglifoz 10 mg Tablet contains Dapagliflozin 10 mg. It belongs to the SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor) class of medicines.

Uses of Siglifoz 10 mg Tablet

Treatment of type 2 diabetes mellitus to improve glycaemic control (as an adjunct to diet and exercise). Also used to reduce risk of hospitalization for heart failure and to slow progression of chronic kidney disease in appropriate patients (as per prescriber advice).

Key benefits

• Lowers blood sugar in type 2 diabetes
• Promotes mild weight loss
• Reduces blood pressure slightly
• Provides heart failure and kidney protection benefits in suitable patients

How Siglifoz 10 mg Tablet works

Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion and lowering blood sugar. It also causes mild diuresis and natriuresis, which can help in heart failure and kidney protection in selected patients.

How to take Siglifoz 10 mg Tablet

Take by mouth once daily, preferably at the same time each day, with or without food. Swallow whole with water. Dose and duration should be as prescribed; maintain adequate hydration and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Siglifoz 10 mg Tablet

Most side effects of Siglifoz are mild and settle as the body adjusts. Reported side effects include:

• Genital fungal infection
• urinary tract infection
• increased urination
• thirst
• dizziness
• low blood pressure
• hypoglycaemia (when used with insulin/sulfonylureas)
• nausea

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Siglifoz 10 mg Tablet

Warnings and precautions

Not for type 1 diabetes. Risk of diabetic ketoacidosis (can occur even with near-normal sugars); seek urgent care for nausea, vomiting, abdominal pain, rapid breathing, confusion. Can cause dehydration/low BP—use caution in elderly, diuretic users, low BP. Genital infections and rare necrotizing fasciitis (Fournier’s gangrene) reported—seek care for genital/perineal pain/swelling/fever. Monitor kidney function; may be ineffective at low eGFR and may need discontinuation as per guidelines. Hold before major surgery/acute illness (sick-day rules) as advised by doctor.

Do not take Siglifoz if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension risk), antihypertensives (additive BP lowering), lithium (may reduce lithium levels), alcohol (increases dehydration/ketosis risk)

How to store Siglifoz 10 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Siglifoz 10 mg Tablet

Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine.

Manufacturer and class

Manufacturer:

VIBHU HEALTHCARE LLP

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor)