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Prescription requiredSerum Institute Of India LtdGYNAECOLOGICAL

Siphene M 25 mg

Clomiphene (25mg)

₹245MRP ₹258In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Siphene M 25 mg is used for female infertility Treatment of Male infertility.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Clomiphene (25mg)
Available variants: 25 mg 30`S
Best price: ₹245
MRP: ₹258
Prescription: Required
Manufacturer: SERUM INTERNATIONAL LTD`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Siphene M 25 mg

Siphene M 25 mg contains Clomiphene (25mg). It belongs to the Hormone preparation class of medicines.

Uses of Siphene M 25 mg

Female infertility Treatment of Male infertility

Key benefits

  • In Treatment of Male infertility Clomiphene helps in the treatment of male infertility by stimulating the production of some hormones that promote the development and release of mature sperm. These hormones play a crucial role in the testes’ function and sperm production. Enhancing hormone levels helps the testes to produce more sperm
  • resulting in a higher sperm count. This improves the chances of successful conception for couples struggling with male infertility issues.

How Siphene M 25 mg works

Siphene -M Tablet increases the release of two hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In females, the increased FSH and LH levels stimulate the growth and maturation of eggs (ovarian follicles), ultimately leading to ovulation. In males, these hormones play a crucial role in stimulating the testes to produce more testosterone and enhance sperm production. Production of good sperm and ovulation is crucial for fertility.

How to take Siphene M 25 mg

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siphene -M Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Siphene -M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine may cause nausea, vomiting and withdrawal bleeding. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Siphene M 25 mg

Most side effects of Siphene M are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Siphene M 25 mg

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Take a hormonal medicine at the same time every day; the effect depends on a steady level. Seek urgent care for sudden chest pain, breathlessness, severe headache, weakness on one side, or pain and swelling in a calf — hormone preparations can raise the risk of clots. Tell your doctor if you smoke, have migraine with aura, high blood pressure, or a family history of clots or breast cancer, before starting. Report any unusual or heavy vaginal bleeding to your doctor.

Do not take Siphene M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a history of blood clots, certain hormone-sensitive cancers, or active liver disease. Several are contraindicated in pregnancy.

Interactions with other medicines

Rifampicin, several anti-epileptics and St John's wort make hormonal contraception unreliable. Tell your doctor about every medicine, supplement and herbal product you take.

How to store Siphene M 25 mg

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Siphene M 25 mg

If you are male and taking Siphene -M Tablet, your doctor may recommend semen analysis tests during the treatment. Follow your doctor's instructions regarding the dosage and schedule for taking Siphene -M Tablet. If you are using Siphene -M Tablet for ovulation induction, your doctor may recommend tracking ovulation at home using ovulation predictor kits or monitoring body temperature. This can help you plan intercourse or any fertility treatments. Clomiphene treatment is often limited to a specific number of cycles. If pregnancy does not occur after a certain number of cycles, your healthcare provider may explore other fertility treatments or interventions.

Manufacturer and class

Manufacturer:
SERUM INTERNATIONAL LTD`
Therapeutic class:
GYNAECOLOGICAL
Drug class:
Hormone preparation
Chemical class:
Stilbenes

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Medicines with the same active ingredient (Clomiphene (25mg)). Ask your doctor or pharmacist before switching brands.

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Siphene M 25 mg FAQs

What is Siphene M 25 mg used for?
Siphene M 25 mg is commonly used for Female infertility Treatment of Male infertility. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Siphene M 25 mg?
Siphene M 25 mg contains Clomiphene (25mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Siphene M 25 mg?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Siphene M 25 mg work?
Siphene -M Tablet increases the release of two hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Is Siphene M 25 mg a prescription medicine?
Yes. Siphene M 25 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Siphene M 25 mg?
The side effects reported most often with Siphene M are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Siphene M 25 mg be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Siphene M.
Can I drink alcohol while taking Siphene M 25 mg?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Siphene M 25 mg?
If you miss a dose of Siphene -M Tablet, take it as soon as possible.
Is Siphene M 25 mg habit forming?
No. Siphene M 25 mg is not known to be habit forming when taken as prescribed.
How much does Siphene M 25 mg cost on PingMeDoc Pharmacy?
Siphene M 25 mg starts at ₹245 (MRP ₹258) on PingMeDoc Pharmacy. Available in 25 mg 30`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Siphene M 25 mg?
Siphene M 25 mg is manufactured by SERUM INTERNATIONAL LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Siphene M 25 mg delivered?
Siphene M 25 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Siphene M 25 mg, Quick facts

Salt
Clomiphene (25mg)
Best price
₹245
MRP
₹258
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Serum Institute Of India Ltd
Manufacturer
SERUM INTERNATIONAL LTD`
Therapeutic class
GYNAECOLOGICAL
Drug class
Hormone preparation
Chemical class
Stilbenes
Action class
Selective Estrogen Receptor Modulators (SERMs)- Ovulation Stimulants
Habit forming
No
Variants
25 mg 30`S
Delivery
Standard across India

References

The information on Siphene M 25 mg is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Siphene M 25 mg.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.