Sitaclass M 50/500 mg Tablet

Composition of Sitaclass M 50/500 mg Tablet

Sitaclass M 50/500 mg Tablet contains Sitagliptin (50mg) + Metformin (500mg). It belongs to the DPP-4 inhibitor and Biguanide class of medicines.

Uses of Sitaclass M 50/500 mg Tablet

Treatment of Type 2 diabetes mellitus

Key benefits

• In Treatment of Type 2 diabetes mellitus Sitaclass M 50mg/500mg Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level
• your risk of getting any of the serious complications of diabetes
• such as kidney damage
• eye damage
• nerve problems
• and loss of limbs
• is also lowered. Additionally
• proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly
• along with appropriate diet and exercise
• will help you live an everyday
• healthy life. You should keep using this medicine for as long as prescribed because it protects your future health. In patients whose blood sugar is not controlled with metformin and another medicine
• this combination may be used along with medicines such as sulfonylureas
• insulin
• or pioglitazone to improve blood sugar control.

How Sitaclass M 50/500 mg Tablet works

Sitaclass M 50mg/500mg Tablet is a combination of two medicines: sitagliptin and metformin. Sitagliptin helps your pancreas produce more insulin, facilitates effective use of insulin by the body, and reduces excess sugar that your liver makes. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.

How to take Sitaclass M 50/500 mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitaclass M 50mg/500mg Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Sitaclass M 50mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sitaclass M 50/500 mg Tablet

Most side effects of Sitaclass M 50/500 mg are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitaclass M 50/500 mg Tablet

Warnings and precautions

Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Sitaclass M 50/500 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Sitaclass M 50/500 mg Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Sitaclass M 50/500 mg Tablet

Take Sitaclass M 50mg/500mg Tablet with food to lower your chance of having an upset stomach. Take it in addition to regular exercise and a healthy diet to lower blood sugar levels. The chances of weight gain and low blood sugar are lower than with other diabetes medicines. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Sitaclass M 50mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

ANTI DIABETIC

Drug class:

DPP-4 inhibitor and Biguanide