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Prescription requiredLarenonANTI DIABETIC

Sitahenz Pm 500 Tablet

Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

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Sitahenz Pm 500 Tablet is used for treatment of Type 2 diabetes mellitus.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)
Available variants: tablet 500mg + 15mg + 100mg 10`S
Best price: ₹159 (₹15.85 per tablet)
MRP: ₹167
Prescription: Required
Manufacturer: LARENON

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Sitahenz Pm 500 Tablet.

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Sitahenz Pm 500 Tablet

tablet - 500mg + 15mg + 100mg - 10 S

₹159

₹15.85 per tablet

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  • Sitazit-Trio 500MG Tab

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Sitahenz Pm 500 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Sitahenz Pm 500 Tablet

Sitahenz Pm 500 Tablet contains Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg). It belongs to the Biguanide, Oral anti-diabetic and DPP-4 inhibitor class of medicines.

Uses of Sitahenz Pm 500 Tablet

Treatment of Type 2 diabetes mellitus

Key benefits

  • In Treatment of Type 2 diabetes mellitus Lowering blood glucose levels is an essential part of managing diabetes. If you can control these levels
  • you can reduce the risk of serious complications of diabetes
  • such as kidney damage
  • eye damage
  • nerve problems
  • and loss of limbs. Taking Sitahenz PM 500mg/15mg/100mg Tablet medicine regularly along with proper diet and exercise will help you live a normal
  • healthy life.

How Sitahenz Pm 500 Tablet works

Sitahenz PM 500mg/15mg/100mg Tablet is a combination of three antidiabetic medications. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels). Pioglitazone works by enhancing cellular responsiveness to insulin and increasing insulin-dependent glucose utilization and disposal. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

How to take Sitahenz Pm 500 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitahenz PM 500mg/15mg/100mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Sitahenz PM 500mg/15mg/100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sitahenz Pm 500 Tablet

Most side effects of Sitahenz Pm are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitahenz Pm 500 Tablet

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol UNSAFE
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CAUTION
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.

Do not take Sitahenz Pm if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.

How to store Sitahenz Pm 500 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Sitahenz Pm 500 Tablet

Prefer taking Sitahenz PM 500mg/15mg/100mg Tablet after a meal or with a snack, as this will reduce the chance of an upset stomach. Sitahenz PM 500mg/15mg/100mg Tablet may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety. If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting. Monitor your blood sugar regularly while taking this medicine. Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.

Manufacturer and class

Manufacturer:
LARENON
Therapeutic class:
ANTI DIABETIC
Drug class:
Biguanide, Oral anti-diabetic and DPP-4 inhibitor

Substitutes for Sitahenz Pm 500 Tablet

Medicines with the same active ingredient (Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Sitahenz Pm 500 Tablet
Sitazit-Trio 500 mg TabletGLENMARK PHARMACEUTICALStablet · 10`S₹1534% cheaper
Sitaverse Mp Forte TabletVERSE LIFESCIENCEStablet · 10`S₹1643% more
Zita Pio Met 500 TabletGLENMARK PHARMACEUTICALStablet · 10`S₹17410% more
Glura Mp 500 TabletERIS LIFE SCIENCES PVT LTDtablet · 10`S₹18215% more
Sitadoc Mp 500 TabletElbrit LIfe Sciencestablet · 15`S₹21435% more
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Sitahenz Pm 500 Tablet FAQs

What is Sitahenz Pm 500 Tablet used for?
Sitahenz Pm 500 Tablet is commonly used for Treatment of Type 2 diabetes mellitus. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Sitahenz Pm 500 Tablet?
Sitahenz Pm 500 Tablet contains Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Sitahenz Pm 500 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Sitahenz Pm 500 Tablet work?
Sitahenz PM 500mg/15mg/100mg Tablet is a combination of three antidiabetic medications.
Is Sitahenz Pm 500 Tablet a prescription medicine?
Yes. Sitahenz Pm 500 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Sitahenz Pm 500 Tablet?
The side effects reported most often with Sitahenz Pm are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Sitahenz Pm 500 Tablet be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Sitahenz Pm.
Can I drink alcohol while taking Sitahenz Pm 500 Tablet?
Alcohol UNSAFE
What if I miss a dose of Sitahenz Pm 500 Tablet?
If you miss a dose of Sitahenz PM 500mg/15mg/100mg Tablet, take it as soon as possible.
Is Sitahenz Pm 500 Tablet habit forming?
No. Sitahenz Pm 500 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Sitahenz Pm 500 Tablet?
Sitazit-Trio 500 mg Tablet has the same active ingredient and strength and is listed from ₹153 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Sitahenz Pm 500 Tablet cost on PingMeDoc Pharmacy?
Sitahenz Pm 500 Tablet starts at ₹159 (MRP ₹167) on PingMeDoc Pharmacy. Available in tablet 500mg + 15mg + 100mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Sitahenz Pm 500 Tablet?
Sitahenz Pm 500 Tablet is manufactured by LARENON. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Sitahenz Pm 500 Tablet delivered?
Sitahenz Pm 500 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Sitahenz Pm 500 Tablet, Quick facts

Salt
Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)
Form
tablet
Best price
₹159 (₹15.85 per tablet)
MRP
₹167
Prescription
Required (Rx)
Schedule
Schedule H
Brand
LARENON
Manufacturer
LARENON
Therapeutic class
ANTI DIABETIC
Drug class
Biguanide, Oral anti-diabetic and DPP-4 inhibitor
Habit forming
No
Variants
tablet 500mg + 15mg + 100mg 10`S
Delivery
Standard across India

References

The information on Sitahenz Pm 500 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Sitahenz Pm 500 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.