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Prescription requiredAnti-diabetic
Sitaptin-M 50/500
Sitagliptin (50mg) + Metformin (500mg)
₹293MRP ₹3085% offIn stock
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Sitaptin-M 50/500 is used for this medicine is used in the treatment of type 2 diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Sitagliptin (50mg) + Metformin (500mg)
Available variants: 1X15
Best price: ₹293
MRP: ₹308
Prescription: Required
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Sitaptin-M 50/500
Sitaptin-M 50/500 contains Sitagliptin (50mg) + Metformin (500mg). It belongs to the DPP-4 inhibitor and Biguanide class of medicines.
Uses of Sitaptin-M 50/500
This medicine is used in the treatment of type 2 diabetes.
Key benefits
- Weight neutral
- Low risk of hypoglycaemia when used alone
- Usually taken once a day
- First-choice medicine for type 2 diabetes
- Does not usually cause weight gain
How Sitaptin-M 50/500 works
This medicine combines 2 active ingredients: Sitagliptin and Metformin. Sitagliptin lowers blood sugar by protecting the natural gut hormones that tell your pancreas to release insulin after a meal, so the effect is strongest when your sugar is highest. Metformin lowers blood sugar by reducing the amount of glucose your liver releases and by helping your muscles respond better to your own insulin. It does not force your pancreas to make more insulin, which is why it rarely causes low blood sugar on its own.
How to take Sitaptin-M 50/500
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Sitaptin-M 50/500
Most side effects of Sitaptin-M 50/500 are mild and settle as the body adjusts. Reported side effects include:
- Headache
- Sore throat
- Blocked or runny nose
- Nausea
- Stomach pain
- Loose motions
- Metallic taste
- Loss of appetite
- Flatulence
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Sitaptin-M 50/500
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.
Do not take Sitaptin-M 50/500 if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Interactions with other medicines
Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.
How to store Sitaptin-M 50/500
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Sitaptin-M 50/500
It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Manufacturer and class
- Therapeutic class:
- Anti-diabetic
- Drug class:
- DPP-4 inhibitor and Biguanide
Substitutes for Sitaptin-M 50/500
Medicines with the same active ingredient (Sitagliptin (50mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Sitaptin-M 50/500 |
|---|---|---|---|
| Galitz M 500 TabletSAAN LAB LLP | tablet · 10`S | ₹94 | 68% cheaper |
| Suitglip -M XR 50/500 mg TabletIPCA LABORATORIES LTD` | tablet · 10`S | ₹103 | 65% cheaper |
| Sitamax M 50/500 mg TabletAJANTA PHARMA | tablet · 10`S | ₹106 | 64% cheaper |
| Sitavas M 50/500 mg TabletCRESHA LIFESCIENCES | tablet · 10S | ₹106 | 64% cheaper |
| Ziasit 100 mg TabletSTATURE LIFE SCIENCES PRIVATE | tablet · 10`S | ₹106 | 64% cheaper |
| Macsita M XR 50/500Macleods Pharmaceuticals Pvt Ltd | 10S | ₹113 | 61% cheaper |
| Sita OD Met 50/500 TabletMacleods Pharmaceuticals Pvt Ltd | tablet · 10`S | ₹114 | 61% cheaper |
| Alsita M 50 TabletALKEM LAB | tablet · 10`S | ₹115 | 61% cheaper |
| Sita OD Msr 100/500 TabletMacleods Pharmaceuticals Pvt Ltd | tablet · 10`S | ₹121 | 58% cheaper |
| Sitaearth M 500 TabletD EARTH PHARMACEUTICALS | tablet · 10`S | ₹127 | 56% cheaper |
| Istamet 50/500 TabletSun Pharmaceutical Industries Ltd | tablet · 15 Tablet | ₹154 | 47% cheaper |
| Ziomet Life 50/500 TabletLIFELINE HEALTHCARE | tablet · 15`S | ₹157 | 46% cheaper |
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Sitaptin-M 50/500 FAQs
What is Sitaptin-M 50/500 used for?
Sitaptin-M 50/500 is commonly used for This medicine is used in the treatment of type 2 diabetes. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Sitaptin-M 50/500?
Sitaptin-M 50/500 contains Sitagliptin (50mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Sitaptin-M 50/500?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Sitaptin-M 50/500 work?
This medicine combines 2 active ingredients: Sitagliptin and Metformin.
Is Sitaptin-M 50/500 a prescription medicine?
Yes. Sitaptin-M 50/500 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Sitaptin-M 50/500?
The side effects reported most often with Sitaptin-M 50/500 are Headache, Sore throat, Blocked or runny nose, Nausea, Stomach pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Sitaptin-M 50/500 be taken during pregnancy?
Consult your doctor before using this in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Sitaptin-M 50/500.
Can I drink alcohol while taking Sitaptin-M 50/500?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Sitaptin-M 50/500?
Take it as soon as you remember.
Is Sitaptin-M 50/500 habit forming?
No. Sitaptin-M 50/500 is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Sitaptin-M 50/500?
Galitz M 500 Tablet has the same active ingredient and strength and is listed from ₹94 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Sitaptin-M 50/500 cost on PingMeDoc Pharmacy?
Sitaptin-M 50/500 starts at ₹293 (MRP ₹308) on PingMeDoc Pharmacy. Available in 1X15. Final price is confirmed at checkout and may vary by variant and location.
How is Sitaptin-M 50/500 delivered?
Sitaptin-M 50/500 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Sitaptin-M 50/500, Quick facts
- Salt
- Sitagliptin (50mg) + Metformin (500mg)
- Best price
- ₹293
- MRP
- ₹308
- Prescription
- Required (Rx)
- Therapeutic class
- Anti-diabetic
- Drug class
- DPP-4 inhibitor and Biguanide
- Habit forming
- No
- Variants
- 1X15
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Sitaptin-M 50/500.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.