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Prescription requiredPharmanovaPAIN ANALGESICS

Tolby D Tablet

Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Isibro D Tablet₹220View
  • Thrize Plus₹290View
  • Zymoflam D Tablet₹309View

Tolby D Tablet is used for pain relief.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)
Available variants: tablet 48mg + 90mg + 100mg + 50mg 10`S
Best price: ₹202 (₹20.21 per tablet)
MRP: ₹213
Prescription: Required
Manufacturer: PHARMANOVA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tolby D Tablet

Tolby D Tablet contains Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Tolby D Tablet

Pain relief

Key benefits

  • In Pain relief Tolby-D Tablet relieves pain
  • reduce swelling and ease inflammation in conditions like rheumatoid arthritis
  • osteoarthritis and ankylosing spondolytis. It also gives relief from muscle and back pain
  • toothache
  • or pain in the ear and throat. It works by reducing substances in the body that causes pain and swelling. Take it as prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better
  • more active
  • quality of life.

How Tolby D Tablet works

Tolby-D Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac. Trypsin and Bromelain are enzymes. They increase blood supply and make the body produce substances that fight pain and swelling. Rutoside is an antioxidant which protects the body from damage by chemicals (free radicals) and further reduces swelling. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) which works by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and inflammation (redness and swelling).

How to take Tolby D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolby-D Tablet is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Tolby-D Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tolby D Tablet

Most side effects of Tolby D are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tolby D Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving CAUTION
KidneyKidney UNSAFE
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Tolby D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Tolby D Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Tolby D Tablet

Tolby-D Tablet helps relieve pain and inflammation that may occur due to trauma, surgery or everyday activity. It may also be used to relieve inflammation in rheumatic and degenerative conditions, such as rheumatoid arthritis and osteoarthritis. Take it with plenty of fluids, an hour before or two hours after a meal. It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor. It may cause dizziness and blurred vision. Do not drive or do anything requiring concentration until you know how it affects you. It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.

Manufacturer and class

Manufacturer:
PHARMANOVA
Therapeutic class:
PAIN ANALGESICS
Drug class:
Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug

Substitutes for Tolby D Tablet

Medicines with the same active ingredient (Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Tolby D Tablet
Isibro D TabletEYSYS PHARMAtablet · 10`S₹2209% more
Thrize PlusPharmed Ltd10`S₹29043% more
Zymoflam D TabletARISTO PHARMACEUTICALS PVT LTDtablet · 10`S₹30953% more
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Tolby D Tablet FAQs

What is Tolby D Tablet used for?
Tolby D Tablet is commonly used for Pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Tolby D Tablet?
Tolby D Tablet contains Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Tolby D Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Tolby D Tablet work?
Tolby-D Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac.
Is Tolby D Tablet a prescription medicine?
Yes. Tolby D Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tolby D Tablet?
The side effects reported most often with Tolby D are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tolby D Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tolby D.
Can I drink alcohol while taking Tolby D Tablet?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Tolby D Tablet?
If you miss a dose of Tolby-D Tablet, take it as soon as possible.
Is Tolby D Tablet habit forming?
No. Tolby D Tablet is not known to be habit forming when taken as prescribed.
How much does Tolby D Tablet cost on PingMeDoc Pharmacy?
Tolby D Tablet starts at ₹202 (MRP ₹213) on PingMeDoc Pharmacy. Available in tablet 48mg + 90mg + 100mg + 50mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tolby D Tablet?
Tolby D Tablet is manufactured by PHARMANOVA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tolby D Tablet delivered?
Tolby D Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Tolby D Tablet, Quick facts

Salt
Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)
Form
tablet
Best price
₹202 (₹20.21 per tablet)
MRP
₹213
Prescription
Required (Rx)
Schedule
Schedule H
Brand
PHARMANOVA
Manufacturer
PHARMANOVA
Therapeutic class
PAIN ANALGESICS
Drug class
Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
tablet 48mg + 90mg + 100mg + 50mg 10`S
Delivery
Standard across India

References

The information on Tolby D Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tolby D Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.