
Acnesol A Nanogel
Systopic Lab - 15 G
Prescription required
Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg)
Vogs GM 2 is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Vogs GM 2 contains Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg). It belongs to the Sulfonylurea, Biguanide and Oral anti-diabetic class of medicines.
Treatment of Type 2 diabetes mellitus
Vogs-GM 2 Tablet SR is a combination of three antidiabetic medicines: glimepiride, metformin, and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor that prevents the breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vogs-GM 2 Tablet SR is to be taken on an empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Vogs-GM 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Vogs GM are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when combined with insulin or a sulfonylurea.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Vogs-GM 2 Tablet SR can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Carry a sugar source with you for immediate relief. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Individuals with severe renal or hepatic impairment should not take Vogs-GM 2 Tablet SR. This medicine works best when used along with proper diet and exercise.
Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Vogs GM 2 |
|---|---|---|---|
| Voglix GM2 TabletBIO REMEDIES | tablet · 15`S | ₹122 | 2% cheaper |
| Volibose Trio 2 TabletSAAN LAB LLP | tablet · 10`S | ₹124 | 1% cheaper |
| Glisimet Trio 2 TabletEYSYS PHARMA | tablet · 10`S | ₹149 | 18% more |
| Vobit R 0.5/0.2 mgLUPIN LAB | 10`S | ₹149 | 19% more |
| Glucoryl Mv Forte 2 TabletALKEM LAB | tablet · 10`S | ₹154 | 23% more |
| K Glim Trio 2 TabletBlue Cross Laboratories Pvt Ltd | tablet · 15 Tablet | ₹164 | 31% more |
| Xmet Trio 500/0.2/2 TabletGLENMARK PHARMACEUTICALS | tablet · 10`S | ₹168 | 34% more |
| Voglibite gm 2/0.2Corona Remedies Pvt Ltd | 10`S | ₹182 | 45% more |
| Azulix Mv 1/0.3 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹190 | 52% more |
| Switglim-Mv 2/0.2 mg TabletAKUMENTIS HEALTHCARE LTD | tablet · 15`S | ₹192 | 53% more |
| Glimy Mv2 TabletDr Reddys Laboratories Ltd | tablet · 10`S | ₹192 | 53% more |
| Glimda Mv 2 TabletCIPLA LIMITED | tablet · 10 Tablet | ₹194 | 54% more |

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The information on Vogs GM 2 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.