Zanocin Oz IV

Composition of Zanocin Oz IV

Zanocin Oz IV contains Ofloxacin 200 mg + Ornidazole 500 mg (in 100 mL IV infusion). It belongs to the Fluoroquinolone antibiotic + Nitroimidazole antiprotozoal/anaerobic antibacterial class of medicines.

Uses of Zanocin Oz IV

• Treatment of mixed bacterial and protozoal infections such as acute infectious diarrhoea
• dysentery
• gastroenteritis
• intra-abdominal and gynecological infections when susceptible organisms are suspected/confirmed.

Key benefits

• Covers mixed bacterial and protozoal gut infections
• Effective against anaerobic organisms
• Helps control infectious diarrhoea/dysentery
• IV option when oral therapy not possible

How Zanocin Oz IV works

Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial DNA replication. Ornidazole is a nitroimidazole that is reduced inside anaerobic/protozoal cells to reactive metabolites that damage DNA, killing the organisms.

How to take Zanocin Oz IV

For intravenous infusion only. Administer as a slow IV infusion over 60–90 minutes (do not give as IV bolus). Dose and duration as prescribed by the doctor; ensure adequate hydration and complete the full course.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Zanocin Oz IV as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Zanocin Oz IV than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Zanocin Oz IV

Most side effects of Zanocin Oz IV are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal pain
• diarrhoea
• headache
• dizziness
• metallic taste
• injection site pain/phlebitis
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zanocin Oz IV

Warnings and precautions

Prescription-only; use only under medical supervision. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), QT prolongation and worsening of myasthenia gravis—stop and seek care if tendon pain, numbness/tingling or severe dizziness occurs. Risk of C. difficile–associated diarrhoea; avoid unnecessary use. Use with caution in elderly, renal impairment (dose adjustment may be needed), history of seizures, heart rhythm disorders, and liver disease. Avoid excessive sunlight/UV (photosensitivity).

Interactions with other medicines

Warfarin/anticoagulants (↑bleeding risk), antiarrhythmics/QT-prolonging drugs (e.g., amiodarone, sotalol, macrolides) (↑QT risk), corticosteroids (↑tendon rupture risk), antidiabetic drugs/insulin (hypo/hyperglycaemia), theophylline/NSAIDs (↑seizure/CNS stimulation risk), lithium (↑levels), cyclosporine (↑toxicity); alcohol with ornidazole may cause disulfiram-like reaction

How to store Zanocin Oz IV

Store below 25°C, protect from light. Do not freeze. Keep in original container; use immediately after opening as per hospital protocol.

Manufacturer and class

Manufacturer:

SUN PHARMA 2

Therapeutic class:

Antibiotic/Antiprotozoal (Anti-infective)

Drug class:

Fluoroquinolone antibiotic + Nitroimidazole antiprotozoal/anaerobic antibacterial