Ziglim Mv 2

Composition of Ziglim Mv 2

Ziglim Mv 2 contains Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg). It belongs to the Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor (combination) class of medicines.

Uses of Ziglim Mv 2

Type 2 diabetes mellitus in adults when diet and exercise alone or single/dual therapy is insufficient; helps control post‑meal and fasting blood glucose

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity
• Reduces carbohydrate absorption after meals
• Helps achieve better HbA1c control

How Ziglim Mv 2 works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin (a biguanide) reduces hepatic glucose production and improves insulin sensitivity. Voglibose (an alpha‑glucosidase inhibitor) delays carbohydrate absorption in the gut to reduce post‑meal glucose spikes.

How to take Ziglim Mv 2

Oral tablet. Take exactly as prescribed, usually once daily with or just after the main meal (often breakfast) to reduce stomach upset and hypoglycaemia risk. Swallow whole; do not crush/chew modified‑release tablets. Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Ziglim-MV 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ziglim Mv 2

Most side effects of Ziglim Mv are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• flatulence
• bloating
• headache
• dizziness
• weight gain

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ziglim Mv 2

Warnings and precautions

Risk of hypoglycaemia (higher with missed meals, strenuous exercise, alcohol, elderly, kidney/liver impairment); metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, abdominal pain, drowsiness. Use caution/avoid in severe renal impairment, severe liver disease, dehydration, severe infection, hypoxia/heart failure. Temporarily stop metformin before/after iodinated contrast and major surgery as advised. Monitor renal function, liver function, and vitamin B12 with long-term metformin.

Do not take Ziglim Mv if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), ACE inhibitors and salicylates (may increase hypoglycaemia), corticosteroids/thiazide diuretics/sympathomimetics (may raise glucose), beta-blockers (mask hypoglycaemia symptoms), cimetidine and other drugs affecting renal tubular secretion (may increase metformin levels), iodinated contrast media (lactic acidosis risk), NSAIDs and some antibiotics (may affect glucose control)

How to store Ziglim Mv 2

Store below 25°C in a cool, dry place; protect from moisture and light; keep in original pack and out of reach of children.

Expert advice for Ziglim Mv 2

Ziglim-MV 2 Tablet SR can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Carry a sugar source with you for immediate relief. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Individuals with severe renal or hepatic impairment should not take Ziglim-MV 2 Tablet SR. This medicine works best when used along with proper diet and exercise.

Manufacturer and class

Manufacturer:

FDC LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor (combination)