Zoryl Mv 1/0.3 Tablet

Composition of Zoryl Mv 1/0.3 Tablet

Zoryl Mv 1/0.3 Tablet contains Glimepiride (2mg) + Metformin (500mg) + Voglibose (0.2mg). It belongs to the Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor class of medicines.

Uses of Zoryl Mv 1/0.3 Tablet

• Type 2 diabetes mellitus (adult) when blood sugar is not adequately controlled with diet
• exercise and/or single/dual oral antidiabetic therapy; helps control post‑meal and fasting glucose

Key benefits

• Lowers fasting and post-meal blood glucose
• Improves overall glycaemic control (HbA1c)
• Reduces post-prandial sugar spikes
• May help reduce insulin resistance
• Convenient combination therapy

How Zoryl Mv 1/0.3 Tablet works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin reduces glucose production in the liver and improves insulin sensitivity. Voglibose inhibits intestinal alpha‑glucosidase enzymes, delaying carbohydrate absorption and reducing post‑meal blood sugar spikes.

How to take Zoryl Mv 1/0.3 Tablet

Tablet for oral use. Usually taken once daily with food (typically with the first main meal) or as directed by the doctor; swallow whole (do not crush/chew if MR/SR). Follow diet/exercise plan and monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zoryl MV 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zoryl Mv 1/0.3 Tablet

Most side effects of Zoryl Mv 1/0.3 are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• dizziness
• headache
• nausea
• vomiting
• diarrhoea
• abdominal pain
• flatulence
• bloating
• loss of appetite
• metallic taste

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zoryl Mv 1/0.3 Tablet

Warnings and precautions

Risk of hypoglycaemia (higher with missed meals, alcohol, excessive exercise, elderly, kidney/liver impairment); metformin may rarely cause lactic acidosis—seek urgent care for fast breathing, severe weakness, abdominal pain, unusual sleepiness. Use caution in renal impairment; periodic kidney function tests advised. Hold metformin component before/after iodinated contrast procedures and major surgery as advised by doctor. Avoid in severe renal failure, severe liver disease, alcohol abuse, diabetic ketoacidosis/type 1 diabetes. Monitor for vitamin B12 deficiency with long-term use.

Do not take Zoryl Mv 1/0.3 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids/diuretics/thyroid hormones (raise glucose), rifampicin (reduces sulfonylurea effect), azole antifungals/macrolides/fluoroquinolones (may increase hypoglycaemia), ACE inhibitors (may enhance glucose-lowering), iodinated contrast media (lactic acidosis risk with metformin), cimetidine (increases metformin levels)

How to store Zoryl Mv 1/0.3 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Zoryl Mv 1/0.3 Tablet

Zoryl MV 2 Tablet SR can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Carry a sugar source with you for immediate relief. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Individuals with severe renal or hepatic impairment should not take Zoryl MV 2 Tablet SR. This medicine works best when used along with proper diet and exercise.

Manufacturer and class

Manufacturer:

INTAS PHARMACEUTICALS`

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor