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Apex Laboratories Ltd - Tablet - 30 S
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Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w gel
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Acnovate Gel is used for treatment of acne vulgaris (pimples), especially inflammatory acne with redness and pus-filled lesions; helps reduce acne-related inflammation and bacterial growth.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Acnovate Gel.
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Acnovate Gel
gel - 1%w/w + 4%w/w - 15 g
₹311
₹20.72 per g
H & H PHARMACEUTICAL PVT LTD · gel - 20 g · Rx
₹165
₹8.23 per g
A substitute contains the same active ingredient (salt), in the same strength, as Acnovate Gel. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Acnovate Gel contains Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w gel. It belongs to the Topical antibiotic + anti-inflammatory (vitamin B3 derivative) class of medicines.
Clindamycin is a topical antibiotic that inhibits bacterial protein synthesis, reducing Cutibacterium acnes and inflammation in acne lesions. Nicotinamide has anti-inflammatory effects and helps reduce sebum-related inflammation, improving acne and redness.
For external use only. Clean and dry the affected area, then apply a thin layer to acne-affected skin 1–2 times daily or as directed by a doctor. Avoid eyes, lips, inside nose and broken/irritated skin; wash hands after application.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Acnovate are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | No known interaction (topical); use with caution with alcohol-based skin products due to irritation |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Stop use and consult a doctor if severe irritation, swelling, or allergic reaction occurs. Prolonged use may contribute to antibiotic resistance; use only for the duration advised. Rarely, topical clindamycin can cause antibiotic-associated diarrhoea/colitis—seek medical help if severe diarrhoea or abdominal cramps occur. Avoid concomitant use with harsh cleansers, alcohol-based products, or abrasive acne agents unless advised.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Topical erythromycin (may reduce effect), neuromuscular blocking agents (clindamycin may enhance blockade), other topical acne medicines/retinoids/benzoyl peroxide (additive irritation)
Store below 25°C in a cool, dry place. Protect from direct light and heat. Keep the cap tightly closed and out of reach of children.
Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.
Medicines with the same active ingredient (Clindamycin 1% w/w + Nicotinamide (Niacinamide) 4% w/w gel). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Acnovate Gel |
|---|---|---|---|
| Cleargel Nico GelH & H PHARMACEUTICAL PVT LTD | gel · 20 Gm | ₹165 | 47% cheaper |

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The information on Acnovate Gel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.