Skip to main content
PingMeDoc
Prescription requiredSkyglow PharmaGASTRO INTESTINAL

Aderef 400 mg

Ademetionine (400mg)

Aderef 400 mg is used for treatment of Liver disease.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

₹748
100% genuine medicinesPharmacist-verified orderDelivered across India

Key details

Salt: Ademetionine (400mg)
Available variants: 400 mg 10`S
Best price: ₹748
Prescription: Required
Manufacturer: SKYGLOW PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Aderef 400 mg

Aderef 400 mg contains Ademetionine (400mg).

Uses of Aderef 400 mg

Treatment of Liver disease

Key benefits

  • In Treatment of Liver disease Aderef 400mg Tablet is used in the management of liver disease
  • including conditions such as intrahepatic cholestasis and chronic liver disorders. It supports the liver’s natural detoxification processes
  • helps restore antioxidant levels like glutathione
  • and improves bile flow. It protects liver cells and promotes their healthy function
  • playing an important role in maintaining overall liver health.

How Aderef 400 mg works

Aderef 400mg Tablet works by helping the liver make and restore important substances that protect its cells. It increases the liver’s natural antioxidants, reduces damage from toxins, and improves the flow of bile. This supports healthier liver function in conditions like intrahepatic cholestasis and chronic liver disease.

How to take Aderef 400 mg

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aderef 400mg Tablet is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Aderef 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

Taking more Aderef than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Aderef 400 mg

Most side effects of Aderef are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Aderef 400 mg

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol CAUTION
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver SAFE IF PRESCRIBED
Habit formingNo

Interactions with other medicines

Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Aderef. Some combinations can change how Aderef works or raise the chance of side effects.

How to store Aderef 400 mg

Store Aderef below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.

Expert advice for Aderef 400 mg

Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools. To make sure it is safe for you, consult with your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting this medicine. Follow a healthy diet, avoid alcohol, and keep yourself well hydrated to complement the treatment. Inform your doctor if you have bipolar disorder or a history of mood swings; this medicine may trigger mania/hypomania. Tell your doctor if you have rare genetic problems affecting methionine metabolism (e.g., homocystinuria). Your doctor may check vitamin B12 and folate levels during treatment.

Manufacturer and class

Manufacturer:
SKYGLOW PHARMA
Therapeutic class:
GASTRO INTESTINAL
Chemical class:
5'- deoxy- 5'- thionucleosides

Substitutes for Aderef 400 mg

Medicines with the same active ingredient (Ademetionine (400mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Aderef 400 mg
Rafahep TabletSAFFRON PHARMACEUTICAtablet · 10`S₹93825% more
See all substitutes and alternatives

More from Skyglow Pharma

View categories
Napzole 40MG Tab
Rx

Napzole 40MG Tab

Skyglow Pharma - Tablet - 40 mg - 15 S

₹113

Prescription required

Enilytrip - 10 Tab
Out of stock

Enilytrip - 10 Tab

Skyglow Pharma - Tablet - 10 S

₹23
RxOut of stock

Eseloz It Caps

Skyglow Pharma - Capsule - 10 S

₹220

Prescription required

RxOut of stock

Exobalin P Caps 10S

Skyglow Pharma - Capsule - 10 S

₹192

Prescription required

Hepgut Cap
RxOut of stock

Hepgut Cap

Skyglow Pharma - Capsule - 10 S

₹136

Prescription required

Out of stock

Immovjoint Tab 10S

Skyglow Pharma - Tablet - 10 S

₹299
Mecotiam Tab 15S
Out of stock

Mecotiam Tab 15S

Skyglow Pharma - Tablet - 15 S

₹267
Mineactive 4G/Sgc
Out of stock

Mineactive 4G/Sgc

Skyglow Pharma - 10 S

₹220

More in Prescription Medicines

View categories
Aeoventa Tab
Rx

Aeoventa Tab

Aeon Pharma Corporation - Tablet - 14 S

₹354

Prescription required

Briv Syrup
Rx

Briv Syrup

Dr Reddys Laboratories Ltd - Syrup - 100 ml

₹446

Prescription required

Calhyp Tab
Rx

Calhyp Tab

Axole Pharma - Tablet - 10 S

₹64

Prescription required

Rx

Car-Key 3.125MG Tab

Beat Pharma - Tablet - 3.125 mg - 10 S

₹48

Prescription required

Carnisure 500 Tablet
Rx

Carnisure 500 Tablet

Torrent Pharmaceuticals Ltd - Tablet - 10 Tablet

₹438

Prescription required

Clomic S Oint
Rx

Clomic S Oint

East West Pharma - Ointment - 15 G

₹98

Prescription required

Rx

Clonil 75 SR

Intas Pharmaceuticals Ltd - 15 S

₹264

Prescription required

Crealap 25K Cap
Rx

Crealap 25K Cap

Walfs Pharma - Capsule - 10 S

₹469

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Etizola Plus 5
RxOut of stock

Etizola Plus 5

Macleods Pharmaceuticals Pvt Ltd - 10 S

₹132

Prescription required

Available in store

In-store
Rx

Etizola Plus 10

Macleods Pharmaceuticals Pvt Ltd - 10 S

₹178

Prescription required

Available in store

In-store
Etizola Lite 5MG
RxOut of stock

Etizola Lite 5MG

Macleods Pharmaceuticals Pvt Ltd - 5 mg - 10 S

₹176

Prescription required

Available in store

In-store
RxOut of stock

Etizola Beta 0.50

Macleods Pharmaceuticals Pvt Ltd - 10 S

₹94

Prescription required

Available in store

In-store
Etizola Beta 0.25
Rx

Etizola Beta 0.25

Macleods Pharmaceuticals Pvt Ltd - 10 S

₹69

Prescription required

Available in store

In-store
Etizola 0.5
Rx

Etizola 0.5

Macleods Pharmaceuticals Pvt Ltd - 15

₹110

Prescription required

Available in store

In-store
Etizola 0.25MG
Rx

Etizola 0.25MG

Macleods Pharmaceuticals Pvt Ltd - 0.25 mg - 15

₹70

Prescription required

Available in store

In-store
Rx

Etirest 0.5 10S

Sun Pharma - 10 S

₹70

Prescription required

Available in store

In-store

Aderef 400 mg FAQs

What is Aderef 400 mg used for?
Aderef 400 mg is commonly used for Treatment of Liver disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Aderef 400 mg?
Aderef 400 mg contains Ademetionine (400mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Aderef 400 mg?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Aderef 400 mg work?
Aderef 400mg Tablet works by helping the liver make and restore important substances that protect its cells.
Is Aderef 400 mg a prescription medicine?
Yes. Aderef 400 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Aderef 400 mg?
The side effects reported most often with Aderef are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Aderef 400 mg be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Aderef.
Can I drink alcohol while taking Aderef 400 mg?
Alcohol CAUTION
What if I miss a dose of Aderef 400 mg?
If you miss a dose of Aderef 400mg Tablet, take it as soon as possible.
Is Aderef 400 mg habit forming?
No. Aderef 400 mg is not known to be habit forming when taken as prescribed.
How much does Aderef 400 mg cost on PingMeDoc Pharmacy?
Aderef 400 mg starts at ₹748 on PingMeDoc Pharmacy. Available in 400 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Aderef 400 mg?
Aderef 400 mg is manufactured by SKYGLOW PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Aderef 400 mg delivered?
Aderef 400 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Aderef 400 mg, Quick facts

Salt
Ademetionine (400mg)
Best price
₹748
Prescription
Required (Rx)
Brand
SKYGLOW PHARMA
Manufacturer
SKYGLOW PHARMA
Therapeutic class
GASTRO INTESTINAL
Chemical class
5'- deoxy- 5'- thionucleosides
Action class
Hepatoprotective Agents
Habit forming
No
Variants
400 mg 10`S
Delivery
Standard across India

References

The information on Aderef 400 mg is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  2. National List of Essential Medicines (NLEM) 2022, Government of India.
  3. Manufacturer's package insert / prescribing information for Aderef 400 mg.
  4. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

More from PingMeDoc™

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.