Enilytrip - 10 Tab
Skyglow Pharma - Tablet - 10 S
₹21.38₹22.50
Save ₹1.12
Prescription requiredSkyglow PharmaGASTRO INTESTINAL
Aderef 400 mg
Ademetionine (400mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
- Rafahep Tablet₹891View
Aderef 400 mg is used for treatment of Liver disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Ademetionine (400mg)
Available variants: 400 mg 10`S
Best price: ₹711
MRP: ₹748
Prescription: Required
Manufacturer: SKYGLOW PHARMA
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Aderef 400 mg
Aderef 400 mg contains Ademetionine (400mg). It belongs to the Liver support agent class of medicines.
Uses of Aderef 400 mg
Treatment of Liver disease
Benefits of Aderef 400 mg
- In Liver disorders
- Aderef supports the liver's recovery and protects its cells from further damage, as part of the treatment your doctor has planned.
- In Fatty liver
- Aderef supports the liver while the fat that has built up is reduced through weight loss and diet, which remain the main treatment.
- In Support of liver function
- Aderef helps the liver carry out its work of processing nutrients and clearing waste while it recovers from illness or strain.
How Aderef 400 mg works
Aderef 400mg Tablet works by helping the liver make and restore important substances that protect its cells. It increases the liver’s natural antioxidants, reduces damage from toxins, and improves the flow of bile. This supports healthier liver function in conditions like intrahepatic cholestasis and chronic liver disease.
How to take Aderef 400 mg
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aderef 400mg Tablet is to be taken on an empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Aderef 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine may cause loose motions and stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Aderef 400 mg
Most side effects of Aderef are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Loose motions
- Nausea
- Stomach discomfort
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Aderef 400 mg
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyCONSULT YOUR DOCTOR
- Consult your doctor before using this in pregnancy.
- Breast feedingCONSULT YOUR DOCTOR
- Consult your doctor before using this while breastfeeding.
- DrivingUNSAFE
- Do not drive or operate machinery while taking this medicine.
- KidneyCAUTION
- Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
Warnings and precautions
A liver supplement does not treat the cause of liver disease. Alcohol, weight, viral hepatitis and medicines are what have to be addressed. Stop alcohol completely if you have any liver condition. Report yellowing of the eyes or skin, dark urine, swelling of the abdomen or confusion without delay. Keep your liver function tests and follow-up appointments.
Do not take Aderef if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Interactions with other medicines
Tell your doctor about every medicine and supplement you take — the liver processes most of them.
How to store Aderef 400 mg
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Aderef 400 mg
- Diarrhea may occur as a side effect.
- Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
- To make sure it is safe for you, consult with your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting this medicine.
- Follow a healthy diet, avoid alcohol, and keep yourself well hydrated to complement the treatment.
- Inform your doctor if you have bipolar disorder or a history of mood swings; this medicine may trigger mania/hypomania.
- Tell your doctor if you have rare genetic problems affecting methionine metabolism (e.g., homocystinuria).
- Your doctor may check vitamin B12 and folate levels during treatment.
Related lab tests
People taking Aderef are often asked to check these from time to time. Your doctor decides which and how often.
Manufacturer and class
- Manufacturer:
- SKYGLOW PHARMA
- Therapeutic class:
- GASTRO INTESTINAL
- Drug class:
- Liver support agent
- Chemical class:
- 5'- deoxy- 5'- thionucleosides
Substitutes for Aderef 400 mg
Medicines with the same active ingredient (Ademetionine (400mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Aderef 400 mg |
|---|---|---|---|
| Rafahep TabletSAFFRON PHARMACEUTICA | tablet · 10`S | ₹891 | 25% more |
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Aderef 400 mg FAQs
What is Aderef 400 mg used for?
Aderef 400 mg is commonly used for Treatment of Liver disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Aderef 400 mg?
Liver disorders: Aderef supports the liver's recovery and protects its cells from further damage, as part of the treatment your doctor has planned. It is also used for fatty liver, support of liver function.
What is the salt in Aderef 400 mg?
Aderef 400 mg contains Ademetionine (400mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Aderef 400 mg?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Aderef 400 mg work?
Aderef 400mg Tablet works by helping the liver make and restore important substances that protect its cells.
Is Aderef 400 mg a prescription medicine?
Yes. Aderef 400 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Aderef 400 mg?
The side effects reported most often with Aderef are Loose motions, Nausea, Stomach discomfort. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Aderef 400 mg be taken during pregnancy?
Consult your doctor before taking Aderef 400 mg in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Aderef.
Can I drink alcohol while taking Aderef 400 mg?
No. Do not drink alcohol while taking Aderef 400 mg.
What if I miss a dose of Aderef 400 mg?
If you miss a dose of Aderef 400mg Tablet, take it as soon as possible.
Is Aderef 400 mg habit forming?
No. Aderef 400 mg is not known to be habit forming when taken as prescribed.
How much does Aderef 400 mg cost on PingMeDoc Pharmacy?
Aderef 400 mg starts at ₹711 (MRP ₹748) on PingMeDoc Pharmacy. Available in 400 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Aderef 400 mg?
Aderef 400 mg is manufactured by SKYGLOW PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Aderef 400 mg delivered?
Aderef 400 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Aderef 400 mg, Quick facts
- Salt
- Ademetionine (400mg)
- Best price
- ₹711
- MRP
- ₹748
- Prescription
- Required (Rx)
- Brand
- SKYGLOW PHARMA
- Manufacturer
- SKYGLOW PHARMA
- Therapeutic class
- GASTRO INTESTINAL
- Drug class
- Liver support agent
- Chemical class
- 5'- deoxy- 5'- thionucleosides
- Action class
- Hepatoprotective Agents
- Habit forming
- No
- Variants
- 400 mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Aderef 400 mg.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.