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Alembic Pharma - Capsule - 10 S
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Prescription requiredAlembic PharmaDERMA
Advan Thf Cream
Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w)
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Advan Thf Cream is used for melasma.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w)
Available variants: cream 2%w/w + 0.025%w/w + 0.01%w/w 15GM
Best price: ₹275 (₹18.32 per g)
MRP: ₹289
Prescription: Required
Manufacturer: ALEMBIC PHARMA
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Advan Thf Cream
Advan Thf Cream contains Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w). It belongs to the Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor class of medicines.
Uses of Advan Thf Cream
Melasma
Benefits of Advan Thf Cream
- In Skin conditions
- Advan Thf treats the skin condition it was prescribed for, relieving itch, redness, dryness or infection so the skin can recover.
- In Skin care
- Advan Thf protects, soothes and maintains the skin as part of a daily routine.
- In Acne
- Advan Thf unblocks pores, reduces the bacteria and inflammation behind spots and helps prevent new ones forming. Improvement is gradual over several weeks.
- In Blackheads and whiteheads
- Advan Thf clears the blocked pores that form blackheads and whiteheads and keeps new ones from forming.
- In Pigmentation
- Advan Thf lightens dark marks left behind by spots, sun exposure or hormonal changes, evening out the skin tone over weeks of regular use.
- In Rough skin
- Advan Thf smooths rough, uneven skin by speeding up the shedding of dead surface cells.
- In Eczema
- Advan Thf calms the inflammation behind an eczema flare, quickly reducing the redness, itch and weeping so the skin can heal and the scratch-itch cycle is broken.
- In Dermatitis
- Advan Thf settles the red, itchy, inflamed skin of dermatitis, whether from an allergy, irritant or contact with something the skin reacts to.
- In Psoriasis
- Advan Thf reduces the thickening, scaling and redness of psoriasis plaques and relieves the itch.
- In Skin inflammation and itching
- Advan Thf relieves itching and inflammation of the skin from insect bites, rashes and reactions, so the skin can settle.
How Advan Thf Cream works
Advan-THF Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.
How to take Advan Thf Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Advan-THF Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Advan Thf Cream
Most side effects of Advan Thf are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Local irritation
- Redness
- Itching
- Dryness
- Peeling
- Burning or stinging
- Increased sensitivity to sunlight
- Thinning of the skin
- Stretch marks
- Acne
- Change in skin colour
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Advan Thf Cream
- AlcoholCAUTION
- Alcohol may worsen the side effects of this medicine. Limit it.
- PregnancyUNSAFE
- Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
- Breast feedingUNSAFE
- Not recommended while breastfeeding.
- DrivingSAFE
- Not expected to affect your ability to drive.
- KidneyCAUTION
- Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
Warnings and precautions
For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds. Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.
Do not take Advan Thf if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.
Interactions with other medicines
No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
How to store Advan Thf Cream
Store at room temperature (below 25°C), protected from heat and direct light. Keep the tube tightly closed and out of reach of children.
Quick tips for Advan Thf Cream
- Along with applying Advan-THF Cream, wear long-sleeved clothing, sunglasses, or a hat whenever you step outside in the hot sun for better protection.
- Do not cover the area being treated with airtight dressings unless instructed by a doctor.
- Use moisturizer regularly to overcome skin dryness during the course of treatment.
- You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation.
- Before using Advan-THF Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.
Manufacturer and class
- Manufacturer:
- ALEMBIC PHARMA
- Therapeutic class:
- DERMA
- Drug class:
- Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor
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Advan Thf Cream FAQs
What is Advan Thf Cream used for?
Advan Thf Cream is commonly used for Melasma. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Advan Thf Cream?
Skin conditions: Advan Thf treats the skin condition it was prescribed for, relieving itch, redness, dryness or infection so the skin can recover. It is also used for skin care, acne, blackheads and whiteheads.
What is the salt in Advan Thf Cream?
Advan Thf Cream contains Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Advan Thf Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Advan Thf Cream work?
Advan-THF Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin).
Is Advan Thf Cream a prescription medicine?
Yes. Advan Thf Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Advan Thf Cream?
The side effects reported most often with Advan Thf are Local irritation, Redness, Itching, Dryness, Peeling. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Advan Thf Cream be taken during pregnancy?
Advan Thf Cream is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Advan Thf.
Can I drink alcohol while taking Advan Thf Cream?
Limit alcohol while taking Advan Thf Cream; it can worsen the side effects.
What if I miss a dose of Advan Thf Cream?
If you miss a dose of Advan-THF Cream, apply it as soon as possible.
Is Advan Thf Cream habit forming?
No. Advan Thf Cream is not known to be habit forming when taken as prescribed.
How much does Advan Thf Cream cost on PingMeDoc Pharmacy?
Advan Thf Cream starts at ₹275 (MRP ₹289) on PingMeDoc Pharmacy. Available in cream 2%w/w + 0.025%w/w + 0.01%w/w 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Advan Thf Cream?
Advan Thf Cream is manufactured by ALEMBIC PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Advan Thf Cream delivered?
Advan Thf Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Advan Thf Cream, Quick facts
- Salt
- Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w)
- Form
- cream
- Best price
- ₹275 (₹18.32 per g)
- MRP
- ₹289
- Prescription
- Required (Rx)
- Brand
- ALEMBIC PHARMA
- Manufacturer
- ALEMBIC PHARMA
- Therapeutic class
- DERMA
- Drug class
- Skin preparation, Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor
- Habit forming
- No
- Variants
- cream 2%w/w + 0.025%w/w + 0.01%w/w 15GM
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- manufacturer labeling/pack information, established medical literature
- Indian pharmacy product databases
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Advan Thf Cream.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.