
Actigut Caps
Alembic Pharma - Capsule - 10 S
Prescription required
Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w)
Advan Thf Cream is used for melasma.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Advan Thf Cream contains Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w).
Melasma
Advan-THF Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Advan-THF Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Advan Thf than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Advan Thf are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding SAFE IF PRESCRIBED |
| Alcohol | No known interaction |
| Driving | Driving |
| Kidney | Kidney |
| Liver | Liver |
| Habit forming | No |
Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Advan Thf. Some combinations can change how Advan Thf works or raise the chance of side effects.
Store at room temperature (below 25°C), protected from heat and direct light. Keep the tube tightly closed and out of reach of children.
Along with applying Advan-THF Cream, wear long-sleeved clothing, sunglasses, or a hat whenever you step outside in the hot sun for better protection. Do not cover the area being treated with airtight dressings unless instructed by a doctor. Use moisturizer regularly to overcome skin dryness during the course of treatment. You may also use certain safe cosmetics (after consulting with your doctor) to lighten pigmentation. Before using Advan-THF Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.

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Prescription required

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The information on Advan Thf Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.