
Albutamol Neo Syrup
Centaur Pharmaceuticals Ltd - Syrup - 100 ml
Prescription required
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Amitriptyline (25mg) + Methylcobalamin (1500mcg)
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Amnuring 25 Tablet is used for neuropathic pain.
Amnuring 25 Tablet contains Amitriptyline (25mg) + Methylcobalamin (1500mcg). It belongs to the Antidepressant and B-complex vitamin class of medicines.
Neuropathic pain
Amitriptyline and methylcobalamin. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amnuring 25 Tablet SR may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Amnuring 25 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Amnuring are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
People taking Amnuring are often asked to check these from time to time. Your doctor decides which and how often.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.