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Prescription requiredExeltis Ordain Health CareCARDIAC

Apresol Plus

Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg)

₹108MRP ₹114In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Apresol Plus is used for treatment of Heart Failure.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg)
Available variants: NA 10`S
Best price: ₹108
MRP: ₹114
Prescription: Required
Manufacturer: EXELTIS ORDAIN HEALTH CARE

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Apresol Plus

Apresol Plus contains Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg). It belongs to the Cardiovascular agent class of medicines.

Uses of Apresol Plus

Treatment of Heart Failure

Key benefits

  • In Treatment of Heart Failure Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness
  • tiredness
  • and swelling in your legs
  • ankles
  • abdomen and other parts of your body. APREsol Plus Tablet makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure. This medicine will help relieve your symptoms
  • making you feel better and more energetic. You should make appropriate lifestyle changes
  • such as eating healthy and keeping active
  • to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

How Apresol Plus works

APREsol Plus Tablet is a combination of two medicines:

How to take Apresol Plus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. APREsol Plus Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of APREsol Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously disturb the heart's rhythm and blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Apresol Plus

Most side effects of Apresol Plus are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Apresol Plus

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol UNSAFE
DrivingDriving CAUTION
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Do not stop or change the dose of a heart medicine on your own. Report fainting, a very slow or very fast pulse, or new breathlessness. Keep every follow-up appointment — most of these medicines need periodic blood tests or an ECG.

Do not take Apresol Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will check that this is suitable for your particular heart condition.

Interactions with other medicines

Heart medicines interact widely. Tell your doctor and pharmacist about everything you take, including herbal products.

How to store Apresol Plus

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Apresol Plus

APREsol Plus Tablet is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier. This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away. APREsol Plus Tablet may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It is best to avoid drinking alcohol while taking APREsol Plus Tablet as it may make the side effects worse. Do not take it in combination with medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure. Do not stop taking APREsol Plus Tablet suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Manufacturer and class

Manufacturer:
EXELTIS ORDAIN HEALTH CARE
Therapeutic class:
CARDIAC
Drug class:
Cardiovascular agent

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Apresol Plus FAQs

What is Apresol Plus used for?
Apresol Plus is commonly used for Treatment of Heart Failure. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Apresol Plus?
Apresol Plus contains Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Apresol Plus?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Apresol Plus work?
APREsol Plus Tablet is a combination of two medicines:
Is Apresol Plus a prescription medicine?
Yes. Apresol Plus is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Apresol Plus?
The side effects reported most often with Apresol Plus are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Apresol Plus be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Apresol Plus.
Can I drink alcohol while taking Apresol Plus?
Alcohol UNSAFE
What if I miss a dose of Apresol Plus?
If you miss a dose of APREsol Plus Tablet, take it as soon as possible.
Is Apresol Plus habit forming?
No. Apresol Plus is not known to be habit forming when taken as prescribed.
How much does Apresol Plus cost on PingMeDoc Pharmacy?
Apresol Plus starts at ₹108 (MRP ₹114) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Apresol Plus?
Apresol Plus is manufactured by EXELTIS ORDAIN HEALTH CARE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Apresol Plus delivered?
Apresol Plus is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Apresol Plus, Quick facts

Salt
Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg)
Best price
₹108
MRP
₹114
Prescription
Required (Rx)
Schedule
Schedule H
Brand
EXELTIS ORDAIN HEALTH CARE
Manufacturer
EXELTIS ORDAIN HEALTH CARE
Therapeutic class
CARDIAC
Drug class
Cardiovascular agent
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Apresol Plus is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Apresol Plus.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.