Cilamet XL 10/50 mg Tablet

Composition of Cilamet XL 10/50 mg Tablet

Cilamet XL 10/50 mg Tablet contains Cilnidipine 10 mg + Metoprolol succinate (extended-release) 50 mg. It belongs to the Calcium channel blocker (dihydropyridine, L/N-type) + Beta-1 selective beta-blocker (extended-release) class of medicines.

Uses of Cilamet XL 10/50 mg Tablet

Treatment of hypertension (high blood pressure); helps reduce risk of cardiovascular events associated with uncontrolled BP

Key benefits

• Lowers high blood pressure
• improves blood vessel relaxation and reduces vascular resistance
• reduces heart rate and cardiac workload
• provides 24-hour BP control with XL metoprolol
• helps reduce risk of heart and stroke complications due to hypertension

How Cilamet XL 10/50 mg Tablet works

Cilnidipine is a calcium channel blocker that relaxes blood vessels by reducing calcium entry into vascular smooth muscle (L- and N-type channel blockade). Metoprolol succinate is a cardioselective beta-1 blocker that lowers heart rate and reduces the force of contraction, decreasing blood pressure and cardiac workload.

How to take Cilamet XL 10/50 mg Tablet

Take orally as advised by the physician, preferably at the same time each day. Swallow the XL/ER tablet whole with water; do not crush or chew. Can be taken with or without food; if it upsets the stomach, take with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a severe fall in blood pressure and a dangerously slow or irregular heartbeat. It can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Cilamet XL 10/50 mg Tablet

Most side effects of Cilamet XL 10/50 mg are mild and settle as the body adjusts. Reported side effects include:

• dizziness
• headache
• fatigue
• slow heart rate (bradycardia)
• low blood pressure
• flushing
• ankle swelling (edema)
• nausea
• cold extremities

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cilamet XL 10/50 mg Tablet

Warnings and precautions

Use with caution in asthma/COPD (beta-blocker may worsen bronchospasm), diabetes (may mask hypoglycaemia symptoms), thyroid disorders, peripheral vascular disease, and kidney/liver impairment. Do not stop metoprolol suddenly (risk of rebound angina/arrhythmia); taper only under medical advice. Monitor BP and pulse; seek care for fainting, very slow pulse, breathing difficulty, or swelling.

Do not take Cilamet XL 10/50 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with very low blood pressure or with severe narrowing of the aortic valve. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma.

Interactions with other medicines

Other antihypertensives/diuretics (additive hypotension), verapamil/diltiazem/amiodarone/digoxin (increased risk of bradycardia/heart block), clonidine (rebound hypertension on withdrawal), NSAIDs (may reduce antihypertensive effect), CYP2D6 inhibitors like fluoxetine/paroxetine/quinidine (increase metoprolol levels), alcohol (may increase dizziness)

How to store Cilamet XL 10/50 mg Tablet

Store below 25°C in a cool, dry place away from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Cilamet XL 10/50 mg Tablet

Raising your legs when sitting, and reducing salt, helps with ankle swelling. Do not stop suddenly without asking your doctor. Take it at the same time each day and do not miss doses. Learn to check your own pulse, and report a persistently slow one.

Manufacturer and class

Manufacturer:

AJANTA PHARMA

Therapeutic class:

Antihypertensive

Drug class:

Calcium channel blocker (dihydropyridine, L/N-type) + Beta-1 selective beta-blocker (extended-release)