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Prescription requiredMankind (pharma)Respiratory (Anti-asthmatic/COPD)

Combihale FF 250 Inhaler

Fluticasone (250mcg) + Formoterol Fumarate (6mcg)

Combihale FF 250 Inhaler is used for maintenance treatment of asthma and COPD to reduce symptoms such as wheeze, breathlessness, chest tightness and to prevent exacerbations.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹905
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Fluticasone (250mcg) + Formoterol Fumarate (6mcg)
Available variants: inhale 120 MDI
Best price: ₹905
Prescription: Required
Manufacturer: Mankind Pharma Ltd

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Combihale FF 250 Inhaler

Combihale FF 250 Inhaler contains Fluticasone (250mcg) + Formoterol Fumarate (6mcg). It belongs to the Inhaled corticosteroid (ICS) + Long-acting beta2-agonist (LABA) class of medicines.

Uses of Combihale FF 250 Inhaler

  • Maintenance treatment of asthma and COPD to reduce symptoms such as wheeze
  • breathlessness
  • chest tightness and to prevent exacerbations.

Key benefits

  • Controls chronic asthma symptoms
  • Reduces airway inflammation
  • Improves breathing and exercise tolerance
  • Helps prevent exacerbations
  • Once-daily maintenance convenience (if applicable)

How Combihale FF 250 Inhaler works

Fluticasone furoate is an inhaled corticosteroid that reduces airway inflammation and hyperresponsiveness. Vilanterol is a long-acting beta2-agonist that relaxes bronchial smooth muscle to keep airways open for prolonged symptom control.

How to take Combihale FF 250 Inhaler

Use by inhalation exactly as prescribed, usually once daily at the same time each day. Not for sudden asthma attacks; keep a rescue inhaler (e.g., salbutamol). Rinse mouth/gargle after each use to reduce oral thrush; ensure correct inhaler technique.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Combihale FF 250 Inhaler

Most side effects of Combihale FF are mild and settle as the body adjusts. Reported side effects include:

  • Hoarseness
  • throat irritation
  • cough
  • headache
  • oral thrush (candidiasis)
  • palpitations
  • tremor

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Combihale FF 250 Inhaler

PregnancyUse with caution
BreastfeedingCombihale FF 250 Inhaler is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholNo known interaction
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

Not a rescue medicine for acute bronchospasm. Increased risk of pneumonia in COPD; monitor for fever, increased sputum or worsening breathlessness. Use with caution in heart rhythm disorders, hypertension, diabetes, hyperthyroidism, glaucoma, and infections (including TB). Do not stop abruptly without medical advice.

Do not take Combihale FF if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) increase steroid exposure; other beta-agonists, MAO inhibitors/TCAs (cardiac effects); beta-blockers may reduce effect; diuretics can increase risk of hypokalemia with LABA.

How to store Combihale FF 250 Inhaler

Store below 25°C, keep dry and protected from moisture/heat. Keep device closed when not in use.

Expert advice for Combihale FF 250 Inhaler

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Digihaler FF 6mcg/250mcg Inhaler is a combination of two medicines that opens the airways and makes it easier to breathe.</li> <li>This medicine is for inhalation only. The tablet should not be swallowed.</li> <li>It should be taken at the same time each day.</li> <li>It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. </li> <li>Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.</li> <li>Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.</li> <li>Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.</li> <li>Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Digihaler FF 6mcg/250mcg Inhaler can lower blood potassium level.</li> <li>Only miniscule amounts of Digihaler FF 6mcg/250mcg Inhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
Mankind Pharma Ltd
Therapeutic class:
Respiratory (Anti-asthmatic/COPD)
Drug class:
Inhaled corticosteroid (ICS) + Long-acting beta2-agonist (LABA)

Substitutes for Combihale FF 250 Inhaler

Medicines with the same active ingredient (Fluticasone (250mcg) + Formoterol Fumarate (6mcg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Combihale FF 250 Inhaler
Combihale Ff250Red CapsuleMANKIND (PHARMA)capsule · 30`S₹47847% cheaper
Formosone 250 InhalerGERMAN REMEDIESinhaler · 120MDI₹9444% more
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Combihale FF 250 Inhaler FAQs

What is Combihale FF 250 Inhaler used for?
Combihale FF 250 Inhaler is commonly used for Maintenance treatment of asthma and COPD to reduce symptoms such as wheeze, breathlessness, chest tightness and to prevent exacerbations. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Combihale FF 250 Inhaler?
Combihale FF 250 Inhaler contains Fluticasone (250mcg) + Formoterol Fumarate (6mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Combihale FF 250 Inhaler?
Use by inhalation exactly as prescribed, usually once daily at the same time each day. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Combihale FF 250 Inhaler work?
Fluticasone furoate is an inhaled corticosteroid that reduces airway inflammation and hyperresponsiveness.
Is Combihale FF 250 Inhaler a prescription medicine?
Yes. Combihale FF 250 Inhaler is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Combihale FF 250 Inhaler?
The side effects reported most often with Combihale FF are Hoarseness, throat irritation, cough, headache, oral thrush (candidiasis). Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Combihale FF 250 Inhaler be taken during pregnancy?
Use with caution Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Combihale FF.
Can I drink alcohol while taking Combihale FF 250 Inhaler?
No known interaction
What if I miss a dose of Combihale FF 250 Inhaler?
Apply it as soon as you remember.
Is Combihale FF 250 Inhaler habit forming?
No. Combihale FF 250 Inhaler is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Combihale FF 250 Inhaler?
Combihale Ff250Red Capsule has the same active ingredient and strength and is listed from ₹478 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Combihale FF 250 Inhaler cost on PingMeDoc Pharmacy?
Combihale FF 250 Inhaler starts at ₹905 on PingMeDoc Pharmacy. Available in inhale 120 MDI. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Combihale FF 250 Inhaler?
Combihale FF 250 Inhaler is manufactured by Mankind Pharma Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Combihale FF 250 Inhaler delivered?
Combihale FF 250 Inhaler is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Combihale FF 250 Inhaler, Quick facts

Salt
Fluticasone (250mcg) + Formoterol Fumarate (6mcg)
Form
inhale
Best price
₹905
Prescription
Required (Rx)
Schedule
Schedule H
Brand
MANKIND (PHARMA)
Manufacturer
Mankind Pharma Ltd
Therapeutic class
Respiratory (Anti-asthmatic/COPD)
Drug class
Inhaled corticosteroid (ICS) + Long-acting beta2-agonist (LABA)
Habit forming
No
Variants
inhale 120 MDI
Delivery
Standard across India

References

The information on Combihale FF 250 Inhaler is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling, established respiratory guidelines (GINA/GOLD), established medical literature
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Combihale FF 250 Inhaler.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.