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Prescription requiredSilomAnti-emetic and Anti-ulcer agent

Coolgi Dsr Capsule

Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg)

₹187MRP ₹1975% offIn stock
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Delivered across India, usually 8–11 days after the order is confirmed. ₹49 delivery, free above ₹999.

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Coolgi Dsr Capsule is used for this medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg)
Available variants: capsule 10mg + 40mg + 20mg 15`S
Best price: ₹187 (₹12.47 per capsule)
MRP: ₹197
Prescription: Required
Manufacturer: SILOM

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Coolgi Dsr Capsule

Coolgi Dsr Capsule contains Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of Coolgi Dsr Capsule

  • Nausea
  • Vomiting
  • Bloating
  • Slow stomach emptying
  • Acidity
  • Acid reflux
  • Stomach ulcer
  • Heartburn

Benefits of Coolgi Dsr Capsule

In Nausea
Coolgi Dsr blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy.
In Vomiting
Coolgi Dsr stops vomiting so that fluids and other medicines stay down, preventing the dehydration that repeated vomiting causes.
In Bloating
Coolgi Dsr helps the stomach empty more quickly, easing the bloating and early fullness that follow a meal.
In Slow stomach emptying
Coolgi Dsr strengthens the stomach's movements so food passes through more normally, relieving nausea, fullness and reflux.
In Acidity
Coolgi Dsr switches off the pumps in the stomach lining that make acid, so there is far less acid to cause burning and discomfort.
In Acid reflux
Coolgi Dsr reduces the acid that rises into the food pipe, relieving heartburn and giving an inflamed food pipe time to heal.
In Stomach ulcer
Coolgi Dsr lowers stomach acid enough for an ulcer to heal and, with antibiotics when needed, helps clear the infection behind it.
In Heartburn
Coolgi Dsr prevents the burning behind the breastbone that comes after meals or at night, so you can eat and sleep comfortably.

How Coolgi Dsr Capsule works

This medicine combines 2 active ingredients: Domperidone and Esomeprazole. Domperidone settles the stomach and blocks the signals that trigger nausea and vomiting, and helps the stomach empty at a normal rate. Esomeprazole switches off the acid pumps in the lining of your stomach, so much less acid is produced and the lining can heal.

How to take Coolgi Dsr Capsule

Swallow the capsule whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it 15 to 30 minutes before meals. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Coolgi Dsr Capsule

Most side effects of Coolgi Dsr are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Dry mouth
  • Drowsiness
  • Headache
  • Loose motions
  • Restlessness
  • Nausea
  • Stomach pain
  • Flatulence

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Coolgi Dsr Capsule

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyCONSULT YOUR DOCTOR
Consult your doctor before using this in pregnancy.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverCONSULT YOUR DOCTOR
Consult your doctor if you have liver disease.

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take Coolgi Dsr if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store Coolgi Dsr Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Coolgi Dsr Capsule

  • Take it shortly before meals for bloating and early fullness.
  • Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.
  • Take it before breakfast, not after a meal.
  • Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking.
  • These do as much as the tablet for reflux.

Manufacturer and class

Manufacturer:
SILOM
Therapeutic class:
Anti-emetic and Anti-ulcer agent
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

Substitutes for Coolgi Dsr Capsule

Medicines with the same active ingredient (Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Coolgi Dsr Capsule
Coolgi SuspensionSILOMsuspension · 150ML₹13130% cheaper
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Coolgi Dsr Capsule FAQs

What is Coolgi Dsr Capsule used for?
Coolgi Dsr Capsule is commonly used for nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Coolgi Dsr Capsule?
Nausea: Coolgi Dsr blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy. It is also used for vomiting, bloating, slow stomach emptying.
What is the salt in Coolgi Dsr Capsule?
Coolgi Dsr Capsule contains Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Coolgi Dsr Capsule?
Swallow the capsule whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Coolgi Dsr Capsule work?
This medicine combines 2 active ingredients: Domperidone and Esomeprazole.
Is Coolgi Dsr Capsule a prescription medicine?
Yes. Coolgi Dsr Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Coolgi Dsr Capsule?
The side effects reported most often with Coolgi Dsr are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Coolgi Dsr Capsule be taken during pregnancy?
Consult your doctor before taking Coolgi Dsr Capsule in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Coolgi Dsr.
Can I drink alcohol while taking Coolgi Dsr Capsule?
No. Do not drink alcohol while taking Coolgi Dsr Capsule.
What if I miss a dose of Coolgi Dsr Capsule?
Take it as soon as you remember.
Is Coolgi Dsr Capsule habit forming?
No. Coolgi Dsr Capsule is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Coolgi Dsr Capsule?
Coolgi Suspension has the same active ingredient and strength and is listed from ₹131 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Coolgi Dsr Capsule cost on PingMeDoc Pharmacy?
Coolgi Dsr Capsule starts at ₹187 (MRP ₹197) on PingMeDoc Pharmacy. Available in capsule 10mg + 40mg + 20mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Coolgi Dsr Capsule?
Coolgi Dsr Capsule is manufactured by SILOM. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Coolgi Dsr Capsule delivered?
Coolgi Dsr Capsule is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Coolgi Dsr Capsule, Quick facts

Salt
Domperidone (10mg) + Esomeprazole (40mg) + Domperidone (20mg)
Form
capsule
Best price
₹187 (₹12.47 per capsule)
MRP
₹197
Prescription
Required (Rx)
Schedule
Schedule H
Brand
SILOM
Manufacturer
SILOM
Therapeutic class
Anti-emetic and Anti-ulcer agent
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
capsule 10mg + 40mg + 20mg 15`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Coolgi Dsr Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.