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Prescription requiredOzone Pharmaceuticals LtdVitamins / Nutritional supplement (Neurotropic vitamins)

Cynocal 16 Rf Injection

Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg)

₹80MRP ₹84In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Cynocal 16 Rf Injection is used for treatment and prevention of vitamin B12/B6 deficiency, peripheral neuropathy (including diabetic neuropathy), neuropathic pain (numbness, tingling, burning), megaloblastic anemia due to B12 deficiency (as adjunct), convalescence and nutritional deficiency states.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg)
Available variants: injection 1000mcg + 100mg + 100mg 5x2ml
Best price: ₹80
MRP: ₹84
Prescription: Required
Manufacturer: OZONE PHARMACEUTICALS LTD

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Cynocal 16 Rf Injection

Cynocal 16 Rf Injection contains Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg). It belongs to the Vitamin B complex (Methylcobalamin + Pyridoxine + Nicotinamide) injection class of medicines.

Uses of Cynocal 16 Rf Injection

  • Treatment and prevention of vitamin B12/B6 deficiency
  • peripheral neuropathy (including diabetic neuropathy)
  • neuropathic pain (numbness
  • tingling
  • burning)
  • megaloblastic anemia due to B12 deficiency (as adjunct)
  • convalescence and nutritional deficiency states

Key benefits

  • Helps repair damaged nerves
  • reduces neuropathic pain and tingling
  • corrects vitamin B12/B6 deficiency
  • supports energy metabolism and recovery

How Cynocal 16 Rf Injection works

Methylcobalamin is the active form of vitamin B12 that supports myelin sheath formation and nerve repair and helps red blood cell formation. Pyridoxine supports neurotransmitter synthesis and nerve function. Nicotinamide replenishes NAD/NADP needed for cellular energy metabolism and tissue repair.

How to take Cynocal 16 Rf Injection

For intramuscular (IM) or slow intravenous (IV) use as advised by a doctor. Dose and frequency depend on deficiency/neuropathy severity; typically given in courses. Do not self-inject; use aseptic technique and administer by a trained professional.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Cynocal-16 RF Injection, please consult your doctor.

If you take too much

An overdose of this medicine is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Cynocal 16 Rf Injection

Most side effects of Cynocal are mild and settle as the body adjusts. Reported side effects include:

  • Injection site pain
  • redness or swelling
  • nausea
  • vomiting
  • dizziness
  • headache
  • flushing
  • diarrhea
  • rash
  • itching

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cynocal 16 Rf Injection

PregnancyConsult doctor
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholUse with caution
DrivingDriving SAFE
KidneyKidney SAFE IF PRESCRIBED
LiverLiver SAFE IF PRESCRIBED
Habit formingNo

Warnings and precautions

Use only under medical supervision. Inform your doctor if you have allergy to any B-vitamins, kidney or liver disease, or low potassium levels. Rare hypersensitivity reactions can occur—seek urgent care for breathing difficulty, facial swelling or severe rash. Long-term/high-dose pyridoxine may itself cause neuropathy; use the prescribed dose only.

Do not take Cynocal if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Levodopa (without carbidopa) may have reduced effect with pyridoxine, Isoniazid, Penicillamine, Phenytoin, Phenobarbital, Primidone, Chloramphenicol (may blunt hematologic response to B12), Metformin and proton pump inhibitors (can reduce B12 levels with long-term use)

How to store Cynocal 16 Rf Injection

Store below 25°C, protect from light, do not freeze. Keep ampoules in original carton; use immediately after opening and discard any unused portion.

Expert advice for Cynocal 16 Rf Injection

Cynocal-16 RF Injection helps treat vitamin B deficiency. Inform your doctor if you are also taking medication for parkinson’s disease such as levodopa. Inform your doctor if you are pregnant or breastfeeding.

Manufacturer and class

Manufacturer:
OZONE PHARMACEUTICALS LTD
Therapeutic class:
Vitamins / Nutritional supplement (Neurotropic vitamins)
Drug class:
Vitamin B complex (Methylcobalamin + Pyridoxine + Nicotinamide) injection

Substitutes for Cynocal 16 Rf Injection

Medicines with the same active ingredient (Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Cynocal 16 Rf Injection
Meganerv Plus 2 ml Injection1X2ML₹8811% more
Homisure Plus InjectionGLADSTONE PHARMA INDIAinjection · 2ML₹12455% more
See all substitutes and alternatives

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Cynocal 16 Rf Injection FAQs

What is Cynocal 16 Rf Injection used for?
Cynocal 16 Rf Injection is commonly used for Treatment and prevention of vitamin B12/B6 deficiency, peripheral neuropathy (including diabetic neuropathy), neuropathic pain (numbness, tingling, burning), megaloblastic anemia due to B12 deficiency (as adjunct), convalescence and nutritional deficiency states. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Cynocal 16 Rf Injection?
Cynocal 16 Rf Injection contains Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Cynocal 16 Rf Injection?
For intramuscular (IM) or slow intravenous (IV) use as advised by a doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Cynocal 16 Rf Injection work?
Methylcobalamin is the active form of vitamin B12 that supports myelin sheath formation and nerve repair and helps red blood cell formation.
Is Cynocal 16 Rf Injection a prescription medicine?
Yes. Cynocal 16 Rf Injection is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Cynocal 16 Rf Injection?
The side effects reported most often with Cynocal are Injection site pain, redness or swelling, nausea, vomiting, dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Cynocal 16 Rf Injection be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Cynocal.
Can I drink alcohol while taking Cynocal 16 Rf Injection?
Use with caution
What if I miss a dose of Cynocal 16 Rf Injection?
If you miss a dose of Cynocal-16 RF Injection, please consult your doctor.
Is Cynocal 16 Rf Injection habit forming?
No. Cynocal 16 Rf Injection is not known to be habit forming when taken as prescribed.
How much does Cynocal 16 Rf Injection cost on PingMeDoc Pharmacy?
Cynocal 16 Rf Injection starts at ₹80 (MRP ₹84) on PingMeDoc Pharmacy. Available in injection 1000mcg + 100mg + 100mg 5x2ml. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Cynocal 16 Rf Injection?
Cynocal 16 Rf Injection is manufactured by OZONE PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Cynocal 16 Rf Injection delivered?
Cynocal 16 Rf Injection is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Cynocal 16 Rf Injection, Quick facts

Salt
Methylcobalamin (1000mcg) + Niacinamide (100mg) + Vitamin B6 (Pyridoxine) (100mg)
Form
injection
Best price
₹80
MRP
₹84
Prescription
Required (Rx)
Brand
OZONE PHARMACEUTICALS LTD
Manufacturer
OZONE PHARMACEUTICALS LTD
Therapeutic class
Vitamins / Nutritional supplement (Neurotropic vitamins)
Drug class
Vitamin B complex (Methylcobalamin + Pyridoxine + Nicotinamide) injection
Habit forming
No
Variants
injection 1000mcg + 100mg + 100mg 5x2ml
Delivery
Standard across India

References

The information on Cynocal 16 Rf Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack information, standard pharmacology references for methylcobalamin, pyridoxine and nicotinamide, established medical literature
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Cynocal 16 Rf Injection.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.