
Aerohale Spacer Inha Dev
German Remedies - 1 S
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Loperamide hydrochloride 4 mg
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
Depotex 4 mg Tablet is used for treatment of acute diarrhea; symptomatic treatment of chronic diarrhea (as advised by doctor); helps reduce stool frequency and urgency.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Depotex 4 mg Tablet contains Loperamide hydrochloride 4 mg. It belongs to the Peripherally acting opioid receptor agonist (antimotility agent) class of medicines.
Treatment of acute diarrhea; symptomatic treatment of chronic diarrhea (as advised by doctor); helps reduce stool frequency and urgency.
Loperamide is an antidiarrheal that acts on opioid receptors in the intestinal wall to reduce gut motility. This slows intestinal transit, allowing more water and electrolytes to be absorbed, making stools firmer and less frequent.
Oral tablet. For acute diarrhea, take as directed by a doctor/label; usually taken after loose stools. Swallow with water; may be taken with or without food. Maintain adequate fluids/ORS. Do not use for more than 48 hours for acute diarrhea unless advised by a doctor.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine may cause bloating and loose motions. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Depotex are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Use with caution / Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Use with caution (may increase dizziness/drowsiness) |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Do not use in children below recommended age/weight without medical advice. Do not use if there is blood in stools, high fever, dysentery, acute ulcerative colitis, antibiotic-associated colitis (C. difficile), or bacterial enterocolitis (e.g., Salmonella/Shigella/Campylobacter). Stop and seek medical help if constipation, abdominal distension, severe abdominal pain, or no improvement within 48 hours. Use with caution in liver disease. Overdose/misuse can cause serious heart rhythm problems (QT prolongation, torsades) and CNS toxicity—do not exceed recommended dose. Ensure rehydration, especially in children and elderly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Probiotics are used with caution in people whose immune system is significantly suppressed.
CYP3A4/CYP2C8 inhibitors (e.g., clarithromycin/erythromycin, ketoconazole/itraconazole, gemfibrozil) may increase loperamide levels; P-gp inhibitors (e.g., quinidine, ritonavir) increase exposure; other QT-prolonging drugs may raise arrhythmia risk; CNS depressants may increase drowsiness.
Store at room temperature (below 25°C), protected from moisture and direct light. Keep in original blister pack and out of reach of children.
Keep up fluids and oral rehydration salts. Return to a normal diet as soon as you can manage it.

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The information on Depotex 4 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.