Diablin M 5/500 mg Tablet

Composition of Diablin M 5/500 mg Tablet

Diablin M 5/500 mg Tablet contains Dapagliflozin 5 mg + Metformin 500 mg (as Metformin Hydrochloride) tablets. It belongs to the SGLT2 inhibitor + Biguanide class of medicines.

Uses of Diablin M 5/500 mg Tablet

Type 2 diabetes mellitus to improve blood glucose control along with diet and exercise; may be used when single-agent therapy is inadequate.

Key benefits

• Lowers HbA1c and fasting/post-meal glucose
• Improves insulin sensitivity and reduces liver glucose output
• Promotes urinary glucose excretion with mild weight benefit
• Low risk of hypoglycaemia when used without insulin/secretagogues

How Diablin M 5/500 mg Tablet works

Dapagliflozin is an SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, increasing urinary glucose excretion and lowering blood sugar. Metformin decreases hepatic glucose production and improves insulin sensitivity, reducing glucose absorption and improving peripheral uptake.

How to take Diablin M 5/500 mg Tablet

Oral tablet. Take as prescribed, usually once or twice daily with meals to reduce stomach upset. Swallow whole with water; do not crush/chew. Maintain adequate hydration and follow diet/exercise advice; monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Diablin M 5/500 mg Tablet

Most side effects of Diablin M 5/500 mg are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• diarrhoea
• abdominal discomfort
• decreased appetite
• headache
• increased urination
• genital fungal infection
• urinary tract infection
• dizziness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Diablin M 5/500 mg Tablet

Warnings and precautions

For type 2 diabetes only (not for type 1 diabetes). Risk of lactic acidosis with metformin (higher in kidney/liver impairment, dehydration, severe infection, alcohol misuse); stop and seek care if unexplained weakness, muscle pain, fast breathing or severe drowsiness occur. Dapagliflozin may cause dehydration/low BP, genital infections, UTIs, and rarely ketoacidosis even with near-normal sugars; seek care for nausea/vomiting, abdominal pain, rapid breathing. Avoid/use with caution in moderate to severe renal impairment; kidney function should be checked before and during treatment. Temporarily withhold during acute illness, poor intake, major surgery, or before iodinated contrast procedures as advised by doctor.

Do not take Diablin M 5/500 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension), ACE inhibitors/ARBs (may increase risk of low BP), corticosteroids and sympathomimetics (may raise glucose), iodinated contrast media (increases lactic acidosis risk with metformin; temporary discontinuation advised), cationic drugs affecting renal tubular secretion (e.g., cimetidine) may increase metformin levels, alcohol (increases lactic acidosis risk)

How to store Diablin M 5/500 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Diablin M 5/500 mg Tablet

Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

PRIMUS PHARMA

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + Biguanide