Doxinate Plus Tablet

Composition of Doxinate Plus Tablet

Doxinate Plus Tablet contains Doxylamine (10mg) + Vitamin B6 (10mg). It belongs to the Anti-emetic / prokinetic and B-complex vitamin class of medicines.

Uses of Doxinate Plus Tablet

Doxinate Tablet is used in the treatment of nausea and vomiting in pregnancy.

Key benefits

• Rapid relief of nausea and vomiting
• Helps bloating and early fullness
• Corrects a deficiency that causes tiredness and nerve symptoms
• Supports the formation of healthy red blood cells
• Generally well tolerated

How Doxinate Plus Tablet works

Doxinate Tablet is a combination of two medicines: Doxylamine and vitamin B6 (pyridoxine), which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties.

How to take Doxinate Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxinate Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Doxinate Plus Tablet

Most side effects of Doxinate Plus are mild and settle as the body adjusts. Reported side effects include:

• Dryness in mouth Constipation Lightheadedness Drowsiness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Doxinate Plus Tablet

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.

Do not take Doxinate Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.

How to store Doxinate Plus Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Doxinate Plus Tablet

Doxinate Tablet is used to treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes.  Take it on an empty stomach with a glass of water. Doxinate Tablet may cause dizziness. Don't drive or do anything requiring concentration until you know how it affects you. Do not take Doxinate Tablet with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents Do not take Doxinate Tablet while breastfeeding.

Manufacturer and class

Manufacturer:

MANEESH PHARMACEUTICAL

Therapeutic class:

Anti-emetic and Vitamin supplement

Drug class:

Anti-emetic / prokinetic and B-complex vitamin